Cholesterol-metabolizing cytochromes P450: implications for cholesterol lowering

door Pikuleva, Irina A.
Gepubliceerd in 2008

Cholesterol Hydroxylating Cytochrome P450 46A1: From Mechanisms of Action to Clinical Applications

door Pikuleva, Irina A., Cartier, Nathalie
Gepubliceerd in Front Aging Neurosci (2021)

Cytochromes P450: Roles in Diseases

door Pikuleva, Irina A., Waterman, Michael R.
Gepubliceerd in 2013

Cholesterol in the retina: the best is yet to come

door Pikuleva, Irina A., Curcio, Christine A.
Gepubliceerd in 2014

Mass Spectrometry Detection of Isolevuglandin Adduction to Specific Protein Residues

door Charvet, Casey D., Pikuleva, Irina A.
Gepubliceerd in Methods Mol Biol (2015)

Cholesterol 24-Hydroxylation by CYP46A1: Benefits of Modulation for Brain Diseases

door Petrov, Alexey M., Pikuleva, Irina A.
Gepubliceerd in Neurotherapeutics (2019)

Inhibition and stimulation of activity of purified recombinant CYP11A1 by therapeutic agents

door Mast, Natalia, Linger, Marlin, Pikuleva, Irina A.
Gepubliceerd in 2012

Drugs and Scaffold That Inhibit Cytochrome P450 27A1 In Vitro and In Vivo

door Lam, Morrie, Mast, Natalia, Pikuleva, Irina A.
Gepubliceerd in Mol Pharmacol (2018)

Mass spectrometry quantification of PICALM and AP180 in human frontal cortex and neural retina

door Chen, Junjun, Pikuleva, Irina A., Turko, Illarion V.
Gepubliceerd in 2013

Marketed Drugs Can Inhibit Cytochrome P450 27A1, a Potential New Target for Breast Cancer Adjuvant Therapy

door Mast, Natalia, Lin, Joseph B., Pikuleva, Irina A.
Gepubliceerd in Mol Pharmacol (2015)

Retinal Cholesterol Content Is Reduced in Simvastatin-Treated Mice Due to Inhibited Local Biosynthesis Albeit Increased Uptake of Serum Cholesterol

door Mast, Natalia, Bederman, Ilya R., Pikuleva, Irina A.
Gepubliceerd in Drug Metab Dispos (2018)

Pathways of cholesterol homeostasis in mouse retina responsive to dietary and pharmacologic treatments

door Zheng, Wenchao, Mast, Natalia, Saadane, Aicha, Pikuleva, Irina A.
Gepubliceerd in J Lipid Res (2015)

Cholesterol Hydroperoxides as Substrates for Cholesterol-Metabolizing Cytochromes P450 and Alternative Sources of 25-Hydroxycholesterol and other Oxysterols

door van Lier, Johan E., Mast, Natalia, Pikuleva, Irina A.
Gepubliceerd in Angew Chem Int Ed Engl (2015)

Structural Basis of Drug Binding to CYP46A1, an Enzyme That Controls Cholesterol Turnover in the Brain

door Mast, Natalia, Charvet, Casey, Pikuleva, Irina A., Stout, C. David
Gepubliceerd in 2010

Binding of a Cyano- and Fluoro-containing Drug Bicalutamide to Cytochrome P450 46A1: UNUSUAL FEATURES AND SPECTRAL RESPONSE

door Mast, Natalia, Zheng, Wenchao, Stout, C. David, Pikuleva, Irina A.
Gepubliceerd in 2013

Antifungal Azoles: Structural Insights into Undesired Tight Binding to Cholesterol-Metabolizing CYP46A1

door Mast, Natalia, Zheng, Wenchao, Stout, C. David, Pikuleva, Irina A.
Gepubliceerd in 2013

The key genes, phosphoproteins, processes, and pathways affected by efavirenz-activated CYP46A1 in the amyloid-decreasing paradigm of efavirenz treatment

door Petrov, Alexey M., Mast, Natalia, Li, Yong, Pikuleva, Irina A.
Gepubliceerd in FASEB J (2019)

Combined use of mass spectrometry and heterologous expression for identification of membrane-interacting peptides in cytochrome P450 46A1 and NADPH-cytochrome P450 oxidoreductase

door Mast, Natalia, Liao, Wei-Li, Pikuleva, Irina A., Turko, Illarion V.
Gepubliceerd in 2009

Studies of membrane topology of mitochondrial cholesterol hydroxylases CYPs 27A1 and 11A1

door Pikuleva, Irina A., Mast, Natalia, Liao, Wei-Li, Turko, Illarion V.
Gepubliceerd in 2008

Histone H3 Ser57 and Thr58 phosphorylation in the brain of 5XFAD mice

door Anderson, Kyle W., Mast, Natalia, Pikuleva, Irina A., Turko, Illarion V.
Gepubliceerd in FEBS Open Bio (2015)