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Cholesterol Hydroxylating Cytochrome P450 46A1: From Mechanisms of Action to Clinical Applications

Cholesterol, an essential component of the brain, and its local metabolism are involved in many neurodegenerative diseases. The blood-brain barrier is impermeable to cholesterol; hence, cholesterol homeostasis in the central nervous system represents a balance between in situ biosynthesis and elimin...

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Bibliografiske detaljer
Udgivet i:Front Aging Neurosci
Main Authors: Pikuleva, Irina A., Cartier, Nathalie
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8297829/
https://ncbi.nlm.nih.gov/pubmed/34305573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.696778
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