Replication-Competent Viruses as Cancer Immunotherapeutics: Emerging Clinical Data

Por Zamarin, Dmitriy, Pesonen, Sari
Publicado no Hum Gene Ther (2015)

Calcium Gluconate in Phosphate Buffered Saline Increases Gene Delivery with Adenovirus Type 5

Por Ahonen, Marko T., Diaconu, Iulia, Pesonen, Sari, Kanerva, Anna, Baumann, Marc, Parviainen, Suvi T., Spiller, Brad, Cerullo, Vincenzo, Hemminki, Akseli
Publicado em 2010

Incomplete but Infectious Vaccinia Virions Are Produced in the Absence of Oncolysis in Feline SCCF1 Cells

Por Parviainen, Suvi, Autio, Karoliina, Vähä-Koskela, Markus, Guse, Kilian, Pesonen, Sari, Rosol, Thomas J., Zhao, Fang, Hemminki, Akseli
Publicado no PLoS One (2015)

Optimized Mouse Model for the Imaging of Tumor Metastasis upon Experimental Therapy

Por Lavilla-Alonso, Sergio, Abo-Ramadan, Usama, Halavaara, Juha, Escutenaire, Sophie, Tatlisumak, Turgut, Saksela, Kalle, Kanerva, Anna, Hemminki, Akseli, Pesonen, Sari
Publicado em 2011

Verapamil Results in Increased Blood Levels of Oncolytic Adenovirus in Treatment of Patients With Advanced Cancer

Por Koski, Anniina, Raki, Mari, Nokisalmi, Petri, Liikanen, Ilkka, Kangasniemi, Lotta, Joensuu, Timo, Kanerva, Anna, Pesonen, Sari, Alemany, Ramon, Hemminki, Akseli
Publicado em 2012

Adenoviruses with an α(v)β integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magnetic resonance imag...

Por Lavilla-Alonso, Sergio, Bauerschmitz, Gerd, Abo-Ramadan, Usama, Halavaara, Juha, Escutenaire, Sophie, Diaconu, Iulia, Tatlisumak, Turgut, Kanerva, Anna, Hemminki, Akseli, Pesonen, Sari
Publicado em 2010

Safety and biodistribution of a double-deleted oncolytic vaccinia virus encoding CD40 ligand in laboratory Beagles

Por Autio, Karoliina, Knuuttila, Anna, Kipar, Anja, Pesonen, Sari, Guse, Kilian, Parviainen, Suvi, Rajamäki, Minna, Laitinen-Vapaavuori, Outi, Vähä-Koskela, Markus, Kanerva, Anna, Hemminki, Akseli
Publicado no Mol Ther Oncolytics (2014)

Oncolytic virotherapy for treatment of breast cancer, including triple-negative breast cancer

Por Bramante, Simona, Koski, Anniina, Liikanen, Ilkka, Vassilev, Lotta, Oksanen, Minna, Siurala, Mikko, Heiskanen, Raita, Hakonen, Tiina, Joensuu, Timo, Kanerva, Anna, Pesonen, Sari, Hemminki, Akseli
Publicado no Oncoimmunology (2015)

Sodium Iodide Symporter SPECT Imaging of a Patient Treated With Oncolytic Adenovirus Ad5/3-Δ24-hNIS

Por Rajecki, Maria, Kangasmäki, Aki, Laasonen, Leena, Escutenaire, Sophie, Hakkarainen, Tanja, Haukka, Jarmo, Ristimäki, Ari, Kairemo, Kalevi, Kangasniemi, Lotta, Kiljunen, Timo, Joensuu, Timo, Pesonen, Sari, Hemminki, Akseli
Publicado em 2011

Ad3-hTERT-E1A, a Fully Serotype 3 Oncolytic Adenovirus, in Patients With Chemotherapy Refractory Cancer

Por Hemminki, Otto, Diaconu, Iulia, Cerullo, Vincenzo, Pesonen, Saila K, Kanerva, Anna, Joensuu, Timo, Kairemo, Kalevi, Laasonen, Leena, Partanen, Kaarina, Kangasniemi, Lotta, Lieber, Andre, Pesonen, Sari, Hemminki, Akseli
Publicado em 2012

The epithelial phenotype confers resistance of ovarian cancer cells to oncolytic adenoviruses

Por Strauss, Robert, Sova, Pavel, Liu, Ying, Li, ZongYi, Tuve, Sebastian, Pritchard, David, Brinkkoetter, Paul, Möller, Thomas, Wildner, Oliver, Pesonen, Sari, Hemminki, Akseli, Urban, Nicole, Drescher, Charles, Lieber, André
Publicado em 2009

Analysis of Epithelial and Mesenchymal Markers in Ovarian Cancer Reveals Phenotypic Heterogeneity and Plasticity

Por Strauss, Robert, Li, Zong-Yi, Liu, Ying, Beyer, Ines, Persson, Jonas, Sova, Pavel, Möller, Thomas, Pesonen, Sari, Hemminki, Akseli, Hamerlik, Petra, Drescher, Charles, Urban, Nicole, Bartek, Jiri, Lieber, André
Publicado em 2011

Correction: Analysis of Epithelial and Mesenchymal Markers in Ovarian Cancer Reveals Phenotypic Heterogeneity and Plasticity

Por Strauss, Robert, Li, Zong-Yi, Liu, Ying, Beyer, Ines, Persson, Jonas, Sova, Pavel, Möller, Thomas, Pesonen, Sari, Hemminki, Akseli, Hamerlik, Petra, Drescher, Charles, Urban, Nicole, Bartek, Jiri, Lieber, André
Publicado em 2011

Antiangiogenic Arming of an Oncolytic Vaccinia Virus Enhances Antitumor Efficacy in Renal Cell Cancer Models

Por Guse, Kilian, Sloniecka, Marta, Diaconu, Iulia, Ottolino-Perry, Kathryn, Tang, Nan, Ng, Calvin, Le Boeuf, Fabrice, Bell, John C., McCart, J. Andrea, Ristimäki, Ari, Pesonen, Sari, Cerullo, Vincenzo, Hemminki, Akseli
Publicado em 2010

Induction of Interferon Pathways Mediates In Vivo Resistance to Oncolytic Adenovirus

Por Liikanen, Ilkka, Monsurrò, Vladia, Ahtiainen, Laura, Raki, Mari, Hakkarainen, Tanja, Diaconu, Iulia, Escutenaire, Sophie, Hemminki, Otto, Dias, João D, Cerullo, Vincenzo, Kanerva, Anna, Pesonen, Sari, Marzioni, Daniela, Colombatti, Marco, Hemminki, Akseli
Publicado em 2011

Oncolytic Adenovirus With Temozolomide Induces Autophagy and Antitumor Immune Responses in Cancer Patients

Por Liikanen, Ilkka, Ahtiainen, Laura, Hirvinen, Mari LM, Bramante, Simona, Cerullo, Vincenzo, Nokisalmi, Petri, Hemminki, Otto, Diaconu, Iulia, Pesonen, Sari, Koski, Anniina, Kangasniemi, Lotta, Pesonen, Saila K, Oksanen, Minna, Laasonen, Leena, Partanen, Kaarina, Joensuu, Timo, Zhao, Fang, Kanerva, Anna, Hemminki, Akseli
Publicado em 2013

Local immunotherapy with ONCOS-102 shapes harmful tumor associated CD68+ macrophages to become beneficial cells that correlate with increased overall survival

Por Pesonen, Sari, Lundin, Johan, Linder, Nina, Turkki, Riku, Ristimäki, Ari, Joensuu, Timo, Kairemo, Kalevi, Partanen, Kaarina, Alanko, Tuomo, Jäger, Elke, Karbach, Julia, Wahle, Claudia, Hemminki, Akseli, Backman, Charlotta, von Euler, Mikael, Hakonen, Tiina, Ranki, Tuuli, Vuolanto, Antti, Jäderberg, Magnus, Zamarin, Dmitry
Publicado no J Immunother Cancer (2015)

Gene expression analysis of tumors demonstrates an induction of Th1 type immune response following intratumoral administration of ONCOS-102 in refractory solid tumor patients

Por Majumder, Mamun, Kumar, Ashwini, Heckman, Caroline, Kankainen, Matti, Pesonen, Sari, Jäger , Elke, Karbach , Julia, Joensuu, Timo, Kairemo, Kalevi, Partanen, Kaarina, Alanko, Tuomo, Hemminki, Akseli, Backman, Charlotta, Dienel, Kasper, von Euler, Mikael, Hakonen, Tiina, Juhila, Juuso, Ranki, Tuuli, Vassilev, Lotta, Vuolanto, Antti, Jaderberg, Magnus
Publicado no J Immunother Cancer (2014)

Immunological Effects of Low-dose Cyclophosphamide in Cancer Patients Treated With Oncolytic Adenovirus

Por Cerullo, Vincenzo, Diaconu, Iulia, Kangasniemi, Lotta, Rajecki, Maria, Escutenaire, Sophie, Koski, Anniina, Romano, Valentina, Rouvinen, Noora, Tuuminen, Tamara, Laasonen, Leena, Partanen, Kaarina, Kauppinen, Satu, Joensuu, Timo, Oksanen, Minna, Holm, Sirkka-Liisa, Haavisto, Elina, Karioja-Kallio, Aila, Kanerva, Anna, Pesonen, Sari, Arstila, Petteri T, Hemminki, Akseli
Publicado em 2011

Local treatment of a pleural mesothelioma tumor with ONCOS-102 induces a systemic antitumor CD8(+) T-cell response, prominent infiltration of CD8(+) lymphocytes and Th1 type polari...

Por Ranki, Tuuli, Joensuu, Timo, Jäger, Elke, Karbach, Julia, Wahle, Claudia, Kairemo, Kalevi, Alanko, Tuomo, Partanen, Kaarina, Turkki, Riku, Linder, Nina, Lundin, Johan, Ristimäki, Ari, Kankainen, Matti, Hemminki, Akseli, Backman, Charlotta, Dienel, Kasper, von Euler, Mikael, Haavisto, Elina, Hakonen, Tiina, Juhila, Juuso, Jaderberg, Magnus, Priha, Petri, Vassilev, Lotta, Vuolanto, Antti, Pesonen, Sari
Publicado no Oncoimmunology (2014)