Induction of Interferon Pathways Mediates In Vivo Resistance to Oncolytic Adenovirus

Oncolytic adenoviruses are an emerging experimental approach for treatment of tumors refractory to available modalities. Although preclinical results have been promising, and clinical safety has been excellent, it is also apparent that tumors can become virus resistant. The resistance mechanisms acq...

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Главные авторы: Liikanen, Ilkka, Monsurrò, Vladia, Ahtiainen, Laura, Raki, Mari, Hakkarainen, Tanja, Diaconu, Iulia, Escutenaire, Sophie, Hemminki, Otto, Dias, João D, Cerullo, Vincenzo, Kanerva, Anna, Pesonen, Sari, Marzioni, Daniela, Colombatti, Marco, Hemminki, Akseli
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2011
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188743/
https://ncbi.nlm.nih.gov/pubmed/21792178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.144
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