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Induction of Interferon Pathways Mediates In Vivo Resistance to Oncolytic Adenovirus
Oncolytic adenoviruses are an emerging experimental approach for treatment of tumors refractory to available modalities. Although preclinical results have been promising, and clinical safety has been excellent, it is also apparent that tumors can become virus resistant. The resistance mechanisms acq...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3188743/ https://ncbi.nlm.nih.gov/pubmed/21792178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.144 |
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