Induction of Interferon Pathways Mediates In Vivo Resistance to Oncolytic Adenovirus

Oncolytic adenoviruses are an emerging experimental approach for treatment of tumors refractory to available modalities. Although preclinical results have been promising, and clinical safety has been excellent, it is also apparent that tumors can become virus resistant. The resistance mechanisms acq...

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Bibliografiska uppgifter
Huvudupphovsmän: Liikanen, Ilkka, Monsurrò, Vladia, Ahtiainen, Laura, Raki, Mari, Hakkarainen, Tanja, Diaconu, Iulia, Escutenaire, Sophie, Hemminki, Otto, Dias, João D, Cerullo, Vincenzo, Kanerva, Anna, Pesonen, Sari, Marzioni, Daniela, Colombatti, Marco, Hemminki, Akseli
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2011
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188743/
https://ncbi.nlm.nih.gov/pubmed/21792178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.144
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