Induction of Interferon Pathways Mediates In Vivo Resistance to Oncolytic Adenovirus

Oncolytic adenoviruses are an emerging experimental approach for treatment of tumors refractory to available modalities. Although preclinical results have been promising, and clinical safety has been excellent, it is also apparent that tumors can become virus resistant. The resistance mechanisms acq...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Liikanen, Ilkka, Monsurrò, Vladia, Ahtiainen, Laura, Raki, Mari, Hakkarainen, Tanja, Diaconu, Iulia, Escutenaire, Sophie, Hemminki, Otto, Dias, João D, Cerullo, Vincenzo, Kanerva, Anna, Pesonen, Sari, Marzioni, Daniela, Colombatti, Marco, Hemminki, Akseli
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2011
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188743/
https://ncbi.nlm.nih.gov/pubmed/21792178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.144
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