Induction of Interferon Pathways Mediates In Vivo Resistance to Oncolytic Adenovirus

Oncolytic adenoviruses are an emerging experimental approach for treatment of tumors refractory to available modalities. Although preclinical results have been promising, and clinical safety has been excellent, it is also apparent that tumors can become virus resistant. The resistance mechanisms acq...

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Main Authors: Liikanen, Ilkka, Monsurrò, Vladia, Ahtiainen, Laura, Raki, Mari, Hakkarainen, Tanja, Diaconu, Iulia, Escutenaire, Sophie, Hemminki, Otto, Dias, João D, Cerullo, Vincenzo, Kanerva, Anna, Pesonen, Sari, Marzioni, Daniela, Colombatti, Marco, Hemminki, Akseli
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2011
Ábhair:
Original Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188743/
https://ncbi.nlm.nih.gov/pubmed/21792178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.144
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