Defects in Innate Immunity Render Breast Cancer Initiating Cells Permissive to Oncolytic Adenovirus

BACKGROUND: Cancer stem cells/initiating cells (CSC/CIC), are thought to exist as a small population in malignant tissues. They are resistant to conventional cancer treatments and possibly underlie post-treatment relapse. The CIC population can be targeted with capsid modified oncolytic adenoviruses...

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Autori principali: Ahtiainen, Laura, Mirantes, Cristina, Jahkola, Tiina, Escutenaire, Sophie, Diaconu, Iulia, Österlund, Pamela, Kanerva, Anna, Cerullo, Vincenzo, Hemminki, Akseli
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974645/
https://ncbi.nlm.nih.gov/pubmed/21079774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013859
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