Chronic Activation of Innate Immunity Correlates With Poor Prognosis in Cancer Patients Treated With Oncolytic Adenovirus

Despite many clinical trials conducted with oncolytic viruses, the exact tumor-level mechanisms affecting therapeutic efficacy have not been established. Currently there are no biomarkers available that would predict the clinical outcome to any oncolytic virus. To assess the baseline immunological p...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Taipale, Kristian, Liikanen, Ilkka, Juhila, Juuso, Turkki, Riku, Tähtinen, Siri, Kankainen, Matti, Vassilev, Lotta, Ristimäki, Ari, Koski, Anniina, Kanerva, Anna, Diaconu, Iulia, Cerullo, Vincenzo, Vähä-Koskela, Markus, Oksanen, Minna, Linder, Nina, Joensuu, Timo, Lundin, Johan, Hemminki, Akseli
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754537/
https://ncbi.nlm.nih.gov/pubmed/26310629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.143
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