Chronic Activation of Innate Immunity Correlates With Poor Prognosis in Cancer Patients Treated With Oncolytic Adenovirus

Despite many clinical trials conducted with oncolytic viruses, the exact tumor-level mechanisms affecting therapeutic efficacy have not been established. Currently there are no biomarkers available that would predict the clinical outcome to any oncolytic virus. To assess the baseline immunological p...

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Bibliografski detalji
Izdano u:Mol Ther
Glavni autori: Taipale, Kristian, Liikanen, Ilkka, Juhila, Juuso, Turkki, Riku, Tähtinen, Siri, Kankainen, Matti, Vassilev, Lotta, Ristimäki, Ari, Koski, Anniina, Kanerva, Anna, Diaconu, Iulia, Cerullo, Vincenzo, Vähä-Koskela, Markus, Oksanen, Minna, Linder, Nina, Joensuu, Timo, Lundin, Johan, Hemminki, Akseli
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754537/
https://ncbi.nlm.nih.gov/pubmed/26310629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.143
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