Biodistribution Analysis of Oncolytic Adenoviruses in Patient Autopsy Samples Reveals Vascular Transduction of Noninjected Tumors and Tissues

In clinical trials with oncolytic adenoviruses, there has been no mortality associated with treatment vectors. Likewise, in the Advanced Therapy Access Program (ATAP), where 290 patients were treated with 10 different viruses, no vector-related mortality was observed. However, as the patient populat...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Koski, Anniina, Bramante, Simona, Kipar, Anja, Oksanen, Minna, Juhila, Juuso, Vassilev, Lotta, Joensuu, Timo, Kanerva, Anna, Hemminki, Akseli
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817914/
https://ncbi.nlm.nih.gov/pubmed/26156245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.125
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