Biodistribution Analysis of Oncolytic Adenoviruses in Patient Autopsy Samples Reveals Vascular Transduction of Noninjected Tumors and Tissues

In clinical trials with oncolytic adenoviruses, there has been no mortality associated with treatment vectors. Likewise, in the Advanced Therapy Access Program (ATAP), where 290 patients were treated with 10 different viruses, no vector-related mortality was observed. However, as the patient populat...

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Vydáno v:Mol Ther
Hlavní autoři: Koski, Anniina, Bramante, Simona, Kipar, Anja, Oksanen, Minna, Juhila, Juuso, Vassilev, Lotta, Joensuu, Timo, Kanerva, Anna, Hemminki, Akseli
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817914/
https://ncbi.nlm.nih.gov/pubmed/26156245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.125
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