Biodistribution Analysis of Oncolytic Adenoviruses in Patient Autopsy Samples Reveals Vascular Transduction of Noninjected Tumors and Tissues

In clinical trials with oncolytic adenoviruses, there has been no mortality associated with treatment vectors. Likewise, in the Advanced Therapy Access Program (ATAP), where 290 patients were treated with 10 different viruses, no vector-related mortality was observed. However, as the patient populat...

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Foilsithe in:Mol Ther
Main Authors: Koski, Anniina, Bramante, Simona, Kipar, Anja, Oksanen, Minna, Juhila, Juuso, Vassilev, Lotta, Joensuu, Timo, Kanerva, Anna, Hemminki, Akseli
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2015
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Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817914/
https://ncbi.nlm.nih.gov/pubmed/26156245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.125
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