Immunological data from cancer patients treated with Ad5/3-E2F-Δ24-GMCSF suggests utility for tumor immunotherapy

Oncolytic viruses that selectively replicate in tumor cells can be used for treatment of cancer. Accumulating data suggests that virus induced oncolysis can enhance anti-tumor immunity and break immune tolerance. To capitalize on the immunogenic nature of oncolysis, we generated a quadruple modified...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Hemminki, Otto, Parviainen, Suvi, Juhila, Juuso, Turkki, Riku, Linder, Nina, Lundin, Johan, Kankainen, Matti, Ristimäki, Ari, Koski, Anniina, Liikanen, Ilkka, Oksanen, Minna, Nettelbeck, Dirk M., Kairemo, Kalevi, Partanen, Kaarina, Joensuu, Timo, Kanerva, Anna, Hemminki, Akseli
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2015
Предметы:
Clinical Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414204/
https://ncbi.nlm.nih.gov/pubmed/25714011
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