Immunological data from cancer patients treated with Ad5/3-E2F-Δ24-GMCSF suggests utility for tumor immunotherapy

Oncolytic viruses that selectively replicate in tumor cells can be used for treatment of cancer. Accumulating data suggests that virus induced oncolysis can enhance anti-tumor immunity and break immune tolerance. To capitalize on the immunogenic nature of oncolysis, we generated a quadruple modified...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Hemminki, Otto, Parviainen, Suvi, Juhila, Juuso, Turkki, Riku, Linder, Nina, Lundin, Johan, Kankainen, Matti, Ristimäki, Ari, Koski, Anniina, Liikanen, Ilkka, Oksanen, Minna, Nettelbeck, Dirk M., Kairemo, Kalevi, Partanen, Kaarina, Joensuu, Timo, Kanerva, Anna, Hemminki, Akseli
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Clinical Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414204/
https://ncbi.nlm.nih.gov/pubmed/25714011
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