Immunological data from cancer patients treated with Ad5/3-E2F-Δ24-GMCSF suggests utility for tumor immunotherapy

Oncolytic viruses that selectively replicate in tumor cells can be used for treatment of cancer. Accumulating data suggests that virus induced oncolysis can enhance anti-tumor immunity and break immune tolerance. To capitalize on the immunogenic nature of oncolysis, we generated a quadruple modified...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hemminki, Otto, Parviainen, Suvi, Juhila, Juuso, Turkki, Riku, Linder, Nina, Lundin, Johan, Kankainen, Matti, Ristimäki, Ari, Koski, Anniina, Liikanen, Ilkka, Oksanen, Minna, Nettelbeck, Dirk M., Kairemo, Kalevi, Partanen, Kaarina, Joensuu, Timo, Kanerva, Anna, Hemminki, Akseli
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Clinical Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414204/
https://ncbi.nlm.nih.gov/pubmed/25714011
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