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Oncolytic adenoviruses: A potent form of tumor immunovirotherapy

The therapeutic efficacy of oncolytic viruses including adenovirus has been thought to depend mostly on direct viral destruction of tumor cells. However, this view has changed with the discovery that oncolysis can also induce innate and antigen-specific adaptive immunity against the tumor. Here we s...

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Detalhes bibliográficos
Main Authors: Cerullo, Vincenzo, Vähä-Koskela, Markus, Hemminki, Akseli
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489766/
https://ncbi.nlm.nih.gov/pubmed/23162778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20172
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