Antiangiogenic Arming of an Oncolytic Vaccinia Virus Enhances Antitumor Efficacy in Renal Cell Cancer Models

Oncolytic vaccinia viruses have shown compelling results in preclinical cancer models and promising preliminary safety and antitumor activity in early clinical trials. However, to facilitate systemic application it would be useful to improve tumor targeting and antitumor efficacy further. Here we re...

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Detalhes bibliográficos
Main Authors: Guse, Kilian, Sloniecka, Marta, Diaconu, Iulia, Ottolino-Perry, Kathryn, Tang, Nan, Ng, Calvin, Le Boeuf, Fabrice, Bell, John C., McCart, J. Andrea, Ristimäki, Ari, Pesonen, Sari, Cerullo, Vincenzo, Hemminki, Akseli
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798339/
https://ncbi.nlm.nih.gov/pubmed/19906926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00692-09
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