Expression of DAI by an oncolytic vaccinia virus boosts the immunogenicity of the virus and enhances antitumor immunity

In oncolytic virotherapy, the ability of the virus to activate the immune system is a key attribute with regard to long-term antitumor effects. Vaccinia viruses bear one of the strongest oncolytic activities among all oncolytic viruses. However, its capacity for stimulation of antitumor immunity is...

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Foilsithe in:Mol Ther Oncolytics
Main Authors: Hirvinen, Mari, Capasso, Cristian, Guse, Kilian, Garofalo, Mariangela, Vitale, Andrea, Ahonen, Marko, Kuryk, Lukasz, Vähä-Koskela, Markus, Hemminki, Akseli, Fortino, Vittorio, Greco, Dario, Cerullo, Vincenzo
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008257/
https://ncbi.nlm.nih.gov/pubmed/27626058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2016.2
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