Expression of DAI by an oncolytic vaccinia virus boosts the immunogenicity of the virus and enhances antitumor immunity

In oncolytic virotherapy, the ability of the virus to activate the immune system is a key attribute with regard to long-term antitumor effects. Vaccinia viruses bear one of the strongest oncolytic activities among all oncolytic viruses. However, its capacity for stimulation of antitumor immunity is...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Ther Oncolytics
Päätekijät: Hirvinen, Mari, Capasso, Cristian, Guse, Kilian, Garofalo, Mariangela, Vitale, Andrea, Ahonen, Marko, Kuryk, Lukasz, Vähä-Koskela, Markus, Hemminki, Akseli, Fortino, Vittorio, Greco, Dario, Cerullo, Vincenzo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008257/
https://ncbi.nlm.nih.gov/pubmed/27626058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2016.2
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