Expression of DAI by an oncolytic vaccinia virus boosts the immunogenicity of the virus and enhances antitumor immunity

In oncolytic virotherapy, the ability of the virus to activate the immune system is a key attribute with regard to long-term antitumor effects. Vaccinia viruses bear one of the strongest oncolytic activities among all oncolytic viruses. However, its capacity for stimulation of antitumor immunity is...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Hirvinen, Mari, Capasso, Cristian, Guse, Kilian, Garofalo, Mariangela, Vitale, Andrea, Ahonen, Marko, Kuryk, Lukasz, Vähä-Koskela, Markus, Hemminki, Akseli, Fortino, Vittorio, Greco, Dario, Cerullo, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008257/
https://ncbi.nlm.nih.gov/pubmed/27626058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2016.2
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