Contributions of Mathematical Modeling of Beta Cells to the Understanding of Beta-Cell Oscillations and Insulin Secretion

por Pedersen, Morten Gram
Publicado 2009

A Biophysical Model of Electrical Activity in Human β-Cells

por Pedersen, Morten Gram
Publicado 2010

On Depolarization-Evoked Exocytosis as a Function of Calcium Entry: Possibilities and Pitfalls

por Pedersen, Morten Gram
Publicado 2011

Homogenization of Heterogeneously Coupled Bistable ODE's—Applied to Excitation Waves in Pancreatic Islets of Langerhans

por Pedersen, Morten Gram
Publicado 2004

Newcomer insulin secretory granules as a highly calcium-sensitive pool

por Pedersen, Morten Gram, Sherman, Arthur
Publicado 2009

Multiscale modelling of insulin secretion during an intravenous glucose tolerance test

por Pedersen, Morten Gram, Cobelli, Claudio
Publicado 2013

Mathematical modelling of local calcium and regulated exocytosis during inhibition and stimulation of glucagon secretion from pancreatic alpha‐cells

por Montefusco, Francesco, Pedersen, Morten Gram
Publicado en J Physiol (2015)

Mathematical Modeling of Interacting Glucose-Sensing Mechanisms and Electrical Activity Underlying Glucagon-Like Peptide 1 Secretion

por Riz, Michela, Pedersen, Morten Gram
Publicado en PLoS Comput Biol (2015)

Spatiotemporal Modeling of Triggering and Amplifying Pathways in GLP-1 Secreting Intestinal L Cells

por Tagliavini, Alessia, Pedersen, Morten Gram
Publicado en Biophys J (2017)

Explicit Theoretical Analysis of How the Rate of Exocytosis Depends on Local Control by Ca(2+) Channels

por Montefusco, Francesco, Pedersen, Morten Gram
Publicado en Comput Math Methods Med (2018)

Wave-Block Due to a Threshold Gradient Underlies Limited Coordination in Pancreatic Islets

por Pedersen, Morten Gram, Sørensen, Mads Peter
Publicado 2008

Intra- and Inter-Islet Synchronization of Metabolically Driven Insulin Secretion

por Pedersen, Morten Gram, Bertram, Richard, Sherman, Arthur
Publicado 2005

Prediabetes: Evaluation of β-Cell Function

por Basu, Ananda, Pedersen, Morten Gram, Cobelli, Claudio
Publicado 2012

Mathematical Modeling of Heterogeneous Electrophysiological Responses in Human β-Cells

por Riz, Michela, Braun, Matthias, Pedersen, Morten Gram
Publicado 2014

Reactive oxygen and nitrogen species disturb Ca(2+) oscillations in insulin-secreting MIN6 β-cells

por Antonucci, Salvatore, Tagliavini, Alessia, Pedersen, Morten Gram
Publicado en Islets (2016)

Complex Patterns of Metabolic and Ca(2+) Entrainment in Pancreatic Islets by Oscillatory Glucose

por Pedersen, Morten Gram, Mosekilde, Erik, Polonsky, Kenneth S., Luciani, Dan S.
Publicado 2013

Concise Whole-Cell Modeling of BK(Ca)-CaV Activity Controlled by Local Coupling and Stoichiometry

por Montefusco, Francesco, Tagliavini, Alessia, Ferrante, Marco, Pedersen, Morten Gram
Publicado en Biophys J (2017)

Statistical Frailty Modeling for Quantitative Analysis of Exocytotic Events Recorded by Live Cell Imaging: Rapid Release of Insulin-Containing Granules Is Impaired in Human Diabeti...

por Cortese, Giuliana, Gandasi, Nikhil R., Barg, Sebastian, Pedersen, Morten Gram
Publicado en PLoS One (2016)

Interaction of Glycolysis and Mitochondrial Respiration in Metabolic Oscillations of Pancreatic Islets

por Bertram, Richard, Satin, Leslie S., Pedersen, Morten Gram, Luciani, Dan S., Sherman, Arthur
Publicado 2007

Calcium Current Inactivation Rather than Pool Depletion Explains Reduced Exocytotic Rate with Prolonged Stimulation in Insulin-Secreting INS-1 832/13 Cells

por Pedersen, Morten Gram, Salunkhe, Vishal Ashok, Svedin, Emma, Edlund, Anna, Eliasson, Lena
Publicado 2014