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Wave-Block Due to a Threshold Gradient Underlies Limited Coordination in Pancreatic Islets

Two models for coupled pancreatic β cells are used to investigate excited wave propagation in spatially inhomogeneous islets of Langerhans. The application concerns spatial variation of glucose concentration across the islet. A comprehensive model of coupled cells shows that wave blocking occurs as...

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Bibliografske podrobnosti
Main Authors: Pedersen, Morten Gram, Sørensen, Mads Peter
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585626/
https://ncbi.nlm.nih.gov/pubmed/19669486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-008-9069-0
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