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Interaction of Glycolysis and Mitochondrial Respiration in Metabolic Oscillations of Pancreatic Islets

Insulin secretion from pancreatic β-cells is oscillatory, with a typical period of 2–7 min, reflecting oscillations in membrane potential and the cytosolic Ca(2+) concentration. Our central hypothesis is that the slow 2–7 min oscillations are due to glycolytic oscillations, whereas faster oscillatio...

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Detalhes bibliográficos
Main Authors: Bertram, Richard, Satin, Leslie S., Pedersen, Morten Gram, Luciani, Dan S., Sherman, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796835/
https://ncbi.nlm.nih.gov/pubmed/17172305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.097154
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