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A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets

The pancreatic islets of Langerhans regulate glucose homeostasis. The loss of insulin-producing β cells within islets results in diabetes, and islet transplantation from cadaveric donors can cure the disease. In vitro production of whole islets, not just β cells, will benefit from a better understan...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Sharon, Nadav, Chawla, Raghav, Mueller, Jonas, Vanderhooft, Jordan, Whitehorn, James Luke, Rosenthal, Benjamin, Gürtler, Mads, Estanboulieh, Ralph R., Shvartsman, Dmitry, Gifford, David K., Trapnell, Cole, Melton, Doug
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705176/
https://ncbi.nlm.nih.gov/pubmed/30661759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.12.003
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