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Explicit Theoretical Analysis of How the Rate of Exocytosis Depends on Local Control by Ca(2+) Channels

Hormones and neurotransmitters are released from cells by calcium-regulated exocytosis, and local coupling between Ca(2+) channels (CaVs) and secretory granules is a key factor determining the exocytosis rate. Here, we devise a methodology based on Markov chain models that allows us to obtain analyt...

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Pubblicato in:Comput Math Methods Med
Autori principali: Montefusco, Francesco, Pedersen, Morten Gram
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261245/
https://ncbi.nlm.nih.gov/pubmed/30607171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/5721097
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