Contributions of Mathematical Modeling of Beta Cells to the Understanding of Beta-Cell Oscillations and Insulin Secretion

by Pedersen, Morten Gram
Published 2009

A Biophysical Model of Electrical Activity in Human β-Cells

by Pedersen, Morten Gram
Published 2010

On Depolarization-Evoked Exocytosis as a Function of Calcium Entry: Possibilities and Pitfalls

by Pedersen, Morten Gram
Published 2011

Homogenization of Heterogeneously Coupled Bistable ODE's—Applied to Excitation Waves in Pancreatic Islets of Langerhans

by Pedersen, Morten Gram
Published 2004

Newcomer insulin secretory granules as a highly calcium-sensitive pool

by Pedersen, Morten Gram, Sherman, Arthur
Published 2009

Multiscale modelling of insulin secretion during an intravenous glucose tolerance test

by Pedersen, Morten Gram, Cobelli, Claudio
Published 2013

Mathematical modelling of local calcium and regulated exocytosis during inhibition and stimulation of glucagon secretion from pancreatic alpha‐cells

by Montefusco, Francesco, Pedersen, Morten Gram
Published in J Physiol (2015)

Mathematical Modeling of Interacting Glucose-Sensing Mechanisms and Electrical Activity Underlying Glucagon-Like Peptide 1 Secretion

by Riz, Michela, Pedersen, Morten Gram
Published in PLoS Comput Biol (2015)

Spatiotemporal Modeling of Triggering and Amplifying Pathways in GLP-1 Secreting Intestinal L Cells

by Tagliavini, Alessia, Pedersen, Morten Gram
Published in Biophys J (2017)

Explicit Theoretical Analysis of How the Rate of Exocytosis Depends on Local Control by Ca(2+) Channels

by Montefusco, Francesco, Pedersen, Morten Gram
Published in Comput Math Methods Med (2018)

Wave-Block Due to a Threshold Gradient Underlies Limited Coordination in Pancreatic Islets

by Pedersen, Morten Gram, Sørensen, Mads Peter
Published 2008

Intra- and Inter-Islet Synchronization of Metabolically Driven Insulin Secretion

by Pedersen, Morten Gram, Bertram, Richard, Sherman, Arthur
Published 2005

Prediabetes: Evaluation of β-Cell Function

by Basu, Ananda, Pedersen, Morten Gram, Cobelli, Claudio
Published 2012

Mathematical Modeling of Heterogeneous Electrophysiological Responses in Human β-Cells

by Riz, Michela, Braun, Matthias, Pedersen, Morten Gram
Published 2014

Reactive oxygen and nitrogen species disturb Ca(2+) oscillations in insulin-secreting MIN6 β-cells

by Antonucci, Salvatore, Tagliavini, Alessia, Pedersen, Morten Gram
Published in Islets (2016)

Complex Patterns of Metabolic and Ca(2+) Entrainment in Pancreatic Islets by Oscillatory Glucose

by Pedersen, Morten Gram, Mosekilde, Erik, Polonsky, Kenneth S., Luciani, Dan S.
Published 2013

Concise Whole-Cell Modeling of BK(Ca)-CaV Activity Controlled by Local Coupling and Stoichiometry

by Montefusco, Francesco, Tagliavini, Alessia, Ferrante, Marco, Pedersen, Morten Gram
Published in Biophys J (2017)

Statistical Frailty Modeling for Quantitative Analysis of Exocytotic Events Recorded by Live Cell Imaging: Rapid Release of Insulin-Containing Granules Is Impaired in Human Diabeti...

by Cortese, Giuliana, Gandasi, Nikhil R., Barg, Sebastian, Pedersen, Morten Gram
Published in PLoS One (2016)

Interaction of Glycolysis and Mitochondrial Respiration in Metabolic Oscillations of Pancreatic Islets

by Bertram, Richard, Satin, Leslie S., Pedersen, Morten Gram, Luciani, Dan S., Sherman, Arthur
Published 2007

Calcium Current Inactivation Rather than Pool Depletion Explains Reduced Exocytotic Rate with Prolonged Stimulation in Insulin-Secreting INS-1 832/13 Cells

by Pedersen, Morten Gram, Salunkhe, Vishal Ashok, Svedin, Emma, Edlund, Anna, Eliasson, Lena
Published 2014