Heritable Transmission of Stress Resistance by High Dietary Glucose in Caenorhabditis elegans

Por Tauffenberger, Arnaud, Parker, J. Alex
Publicado em 2014

Worming forward: amyotrophic lateral sclerosis toxicity mechanisms and genetic interactions in Caenorhabditis elegans

Por Therrien, Martine, Parker, J. Alex
Publicado em 2014

Deciphering genetic interactions between ALS genes using C. elegans

Por Therrien, Martine, Parker, J Alex
Publicado em 2014

Fragile lifespan expansion by dietary mitohormesis in C. elegans

Por Tauffenberger, Arnaud, Vaccaro, Alexandra, Parker, J. Alex
Publicado no Aging (Albany NY) (2016)

TDP-43 Toxicity Proceeds via Calcium Dysregulation and Necrosis in Aging Caenorhabditis elegans Motor Neurons

Por Aggad, Dina, Vérièpe, Julie, Tauffenberger, Arnaud, Parker, J. Alex
Publicado no J Neurosci (2014)

Deletion of C9ORF72 Results in Motor Neuron Degeneration and Stress Sensitivity in C. elegans

Por Therrien, Martine, Rouleau, Guy A., Dion, Patrick A., Parker, J. Alex
Publicado em 2013

FET proteins regulate lifespan and neuronal integrity

Por Therrien, Martine, Rouleau, Guy A., Dion, Patrick A., Parker, J. Alex
Publicado no Sci Rep (2016)

Glucose delays age-dependent proteotoxicity

Por Tauffenberger, Arnaud, Vaccaro, Alexandra, Aulas, Anais, Velde, Christine Vande, Parker, J Alex
Publicado em 2012

Mutant TDP-43 and FUS Cause Age-Dependent Paralysis and Neurodegeneration in C. elegans

Por Vaccaro, Alexandra, Tauffenberger, Arnaud, Aggad, Dina, Rouleau, Guy, Drapeau, Pierre, Parker, J. Alex
Publicado em 2012

Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death

Por Parker, J. Alex, Connolly, John B., Wellington, Cheryll, Hayden, Michael, Dausset, Jean, Neri, Christian
Publicado em 2001

TDP-1/TDP-43 Regulates Stress Signaling and Age-Dependent Proteotoxicity in Caenorhabditis elegans

Por Vaccaro, Alexandra, Tauffenberger, Arnaud, Ash, Peter E. A., Carlomagno, Yari, Petrucelli, Leonard, Parker, J. Alex
Publicado em 2012

Insulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neurons

Por Scerbak, Courtney, Vayndorf, Elena M., Parker, J. Alex, Neri, Christian, Driscoll, Monica, Taylor, Barbara E.
Publicado em 2014

Fishing for causes and cures of motor neuron disorders

Por Patten, Shunmoogum A., Armstrong, Gary A. B., Lissouba, Alexandra, Kabashi, Edor, Parker, J. Alex, Drapeau, Pierre
Publicado em 2014

Methylene Blue Protects against TDP-43 and FUS Neuronal Toxicity in C. elegans and D. rerio

Por Vaccaro, Alexandra, Patten, Shunmoogum A., Ciura, Sorana, Maios, Claudia, Therrien, Martine, Drapeau, Pierre, Kabashi, Edor, Parker, J. Alex
Publicado em 2012

G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA

Por Aulas, Anaïs, Caron, Guillaume, Gkogkas, Christos G., Mohamed, Nguyen-Vi, Destroismaisons, Laurie, Sonenberg, Nahum, Leclerc, Nicole, Parker, J. Alex, Vande Velde, Christine
Publicado no J Cell Biol (2015)

Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis

Por Vayndorf, Elena M, Scerbak, Courtney, Hunter, Skyler, Neuswanger, Jason R, Toth, Marton, Parker, J Alex, Neri, Christian, Driscoll, Monica, Taylor, Barbara E
Publicado no NPJ Aging Mech Dis (2016)

Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons

Por Lejeune, François-Xavier, Mesrob, Lilia, Parmentier, Frédéric, Bicep, Cedric, Vazquez-Manrique, Rafael P, Parker, J Alex, Vert, Jean-Philippe, Tourette, Cendrine, Neri, Christian
Publicado em 2012

Integration of β-Catenin, Sirtuin, and FOXO Signaling Protects from Mutant Huntingtin Toxicity

Por Parker, J. Alex, Vazquez-Manrique, Rafael P., Tourette, Cendrine, Farina, Francesca, Offner, Nicolas, Mukhopadhyay, Arnab, Orfila, Anne-Marie, Darbois, Aurélie, Menet, Sophie, Tissenbaum, Heidi A., Neri, Christian
Publicado em 2012

C. elegans Neurons Jettison Protein Aggregates and Mitochondria Under Neurotoxic Stress

Por Melentijevic, Ilija, Toth, Marton L., Arnold, Meghan L., Guasp, Ryan J., Harinath, Girish, Nguyen, Ken C., Taub, Daniel, Parker, J. Alex, Neri, Christian, Gabel, Christopher, Hall, David H., Driscoll, Monica
Publicado no Nature (2017)

Conserved pharmacological rescue of hereditary spastic paraplegia-related phenotypes across model organisms

Por Julien, Carl, Lissouba, Alexandra, Madabattula, Surya, Fardghassemi, Yasmin, Rosenfelt, Cory, Androschuk, Alaura, Strautman, Joel, Wong, Clement, Bysice, Andrew, O'sullivan, Julia, Rouleau, Guy A., Drapeau, Pierre, Parker, J. Alex, Bolduc, François V.
Publicado no Hum Mol Genet (2016)