Methylene Blue Protects against TDP-43 and FUS Neuronal Toxicity in C. elegans and D. rerio

The DNA/RNA-binding proteins TDP-43 and FUS are found in protein aggregates in a growing number of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and related dementia, but little is known about the neurotoxic mechanisms. We have generated Caenorhabditis elegans and zebrafi...

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Detaylı Bibliyografya
Asıl Yazarlar: Vaccaro, Alexandra, Patten, Shunmoogum A., Ciura, Sorana, Maios, Claudia, Therrien, Martine, Drapeau, Pierre, Kabashi, Edor, Parker, J. Alex
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407135/
https://ncbi.nlm.nih.gov/pubmed/22848727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042117
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