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Rethinking ALS: the FUS about TDP-43
Mutation in TDP-43, a DNA/RNA binding protein, causes an inherited form of Amyotrophic Lateral Sclerosis (ALS). Combination of its mislocalization in most incidences of sporadic ALS (as well as other neurodegenerative disorders) with discovery of ALS-causing mutations in FUS/TLS, another DNA/RNA bin...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110083/ https://ncbi.nlm.nih.gov/pubmed/19303844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.03.006 |
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