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Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis

Understanding cellular outcomes, such as neuronal remodeling, that are common to both healthy and diseased aging brains is essential to the development of successful brain aging strategies. Here, we used Caenorhabdits elegans to investigate how the expression of proteotoxic triggers, such as polyglu...

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Detalhes bibliográficos
Publicado no:NPJ Aging Mech Dis
Main Authors: Vayndorf, Elena M, Scerbak, Courtney, Hunter, Skyler, Neuswanger, Jason R, Toth, Marton, Parker, J Alex, Neri, Christian, Driscoll, Monica, Taylor, Barbara E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920063/
https://ncbi.nlm.nih.gov/pubmed/27347427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjamd.2016.1
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