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Morphological remodeling of C. elegans neurons during aging is modified by compromised protein homeostasis

Understanding cellular outcomes, such as neuronal remodeling, that are common to both healthy and diseased aging brains is essential to the development of successful brain aging strategies. Here, we used Caenorhabdits elegans to investigate how the expression of proteotoxic triggers, such as polyglu...

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Bibliografiska uppgifter
I publikationen:NPJ Aging Mech Dis
Huvudupphovsmän: Vayndorf, Elena M, Scerbak, Courtney, Hunter, Skyler, Neuswanger, Jason R, Toth, Marton, Parker, J Alex, Neri, Christian, Driscoll, Monica, Taylor, Barbara E
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920063/
https://ncbi.nlm.nih.gov/pubmed/27347427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjamd.2016.1
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