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Worming forward: amyotrophic lateral sclerosis toxicity mechanisms and genetic interactions in Caenorhabditis elegans

Neurodegenerative diseases share pathogenic mechanisms at the cellular level including protein misfolding, excitotoxicity and altered RNA homeostasis among others. Recent advances have shown that the genetic causes underlying these pathologies overlap, hinting at the existence of a genetic network f...

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Bibliografski detalji
Glavni autori: Therrien, Martine, Parker, J. Alex
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029022/
https://ncbi.nlm.nih.gov/pubmed/24860590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00085
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