21st Century Cell Culture for 21st Century Toxicology

von Pamies, David, Hartung, Thomas
Veröffentlicht in Chem Res Toxicol (2016)

Biological and medical applications of a brain-on-a-chip

von Pamies, David, Hartung, Thomas, Hogberg, Helena T
Veröffentlicht in Exp Biol Med (Maywood) (2014)

Organotypic Models to Study Human Glioblastoma: Studying the Beast in Its Ecosystem

von Pamies, David, Zurich, Marie-Gabrielle, Hartung, Thomas
Veröffentlicht in iScience (2020)

In vitro and in silico Models to Study Mosquito-Borne Flavivirus Neuropathogenesis, Prevention, and Treatment

von Chesnut, Megan, Muñoz, Laura S., Harris, Georgina, Freeman, Dana, Gama, Lucio, Pardo, Carlos A., Pamies, David
Veröffentlicht in Front Cell Infect Microbiol (2019)

A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine

von Plummer, Simon, Wallace, Stephanie, Ball, Graeme, Lloyd, Roslyn, Schiapparelli, Paula, Quiñones-Hinojosa, Alfredo, Hartung, Thomas, Pamies, David
Veröffentlicht in Sci Rep (2019)

Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheres

von Abreu, Celina Monteiro, Gama, Lucio, Krasemann, Susanne, Chesnut, Megan, Odwin-Dacosta, Shelly, Hogberg, Helena T., Hartung, Thomas, Pamies, David
Veröffentlicht in Front Microbiol (2018)

Genomic and Phenotypic Alterations of the Neuronal-Like Cells Derived from Human Embryonal Carcinoma Stem Cells (NT2) Caused by Exposure to Organophosphorus Compounds Paraoxon and...

von Pamies, David, Sogorb, Miguel A., Fabbri, Marco, Gribaldo, Laura, Collotta, Angelo, Scelfo, Bibiana, Vilanova, Eugenio, Harris, Georgina, Bal-Price, Anna
Veröffentlicht 2014

Toward a 3D model of human brain development for studying gene/environment interactions

von Hogberg, Helena T, Bressler, Joseph, Christian, Kimberly M, Harris, Georgina, Makri, Georgia, O'Driscoll, Cliona, Pamies, David, Smirnova, Lena, Wen, Zhexing, Hartung, Thomas
Veröffentlicht 2013

Gene–Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres

von Modafferi, Sergio, Zhong, Xiali, Kleensang, Andre, Murata, Yohei, Fagiani, Francesca, Pamies, David, Hogberg, Helena T., Calabrese, Vittorio, Lachman, Herbert, Hartung, Thomas, Smirnova, Lena
Veröffentlicht in Environ Health Perspect (2021)

t(4) report(): Supporting Read-Across Using Biological Data

von Zhu, Hao, Bouhifd, Mounir, Kleinstreuer, Nicole, Kroese, E. Dinant, Liu, Zhichao, Luechtefeld, Thomas, Pamies, David, Shen, Jie, Strauss, Volker, Wu, Shengde, Hartung, Thomas
Veröffentlicht in ALTEX (2016)

Rotenone exerts developmental neurotoxicity in a human brain spheroid model

von Pamies, David, Block, Katharina, Lau, Pierre, Gribaldo, Laura, Pardo, Carlos A., Barreras, Paula, Smirnova, Lena, Wiersma, Daphne, Zhao, Liang, Harris, Georgina, Hartung, Thomas, Hogberg, Helena T.
Veröffentlicht in Toxicol Appl Pharmacol (2018)

Suitability of 3D human brain spheroid models to distinguish toxic effects of gold and poly-lactic acid nanoparticles to assess biocompatibility for brain drug delivery

von Leite, Paulo Emílio Corrêa, Pereira, Mariana Rodrigues, Harris, Georgina, Pamies, David, dos Santos, Lisia Maria Gobbo, Granjeiro, José Mauro, Hogberg, Helena T., Hartung, Thomas, Smirnova, Lena
Veröffentlicht in Part Fibre Toxicol (2019)

Neuroinflammatory Response to TNFα and IL1β Cytokines Is Accompanied by an Increase in Glycolysis in Human Astrocytes In Vitro

von Pamies, David, Sartori, Chiara, Schvartz, Domitille, González-Ruiz, Víctor, Pellerin, Luc, Nunes, Carolina, Tavel, Denise, Maillard, Vanille, Boccard, Julien, Rudaz, Serge, Sanchez, Jean-Charles, Zurich, Marie-Gabrielle
Veröffentlicht in Int J Mol Sci (2021)

Toxicity, recovery, and resilience in a 3D dopaminergic neuronal in vitro model exposed to rotenone

von Harris, Georgina, Eschment, Melanie, Orozco, Sebastian Perez, McCaffery, J. Michael, Maclennan, Richard, Severin, Daniel, Leist, Marcel, Kleensang, Andre, Pamies, David, Maertens, Alexandra, Hogberg, Helena T., Freeman, Dana, Kirkwood, Alfredo, Hartung, Thomas, Smirnova, Lena
Veröffentlicht in Arch Toxicol (2018)

Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model

von Zhong, Xiali, Harris, Georgina, Smirnova, Lena, Zufferey, Valentin, Sá, Rita de Cássia da Silveira e, Baldino Russo, Fabiele, Baleeiro Beltrao Braga, Patricia Cristina, Chesnut, Megan, Zurich, Marie-Gabrielle, Hogberg, Helena T., Hartung, Thomas, Pamies, David
Veröffentlicht in Front Cell Neurosci (2020)

t(4) Workshop Report(): Quality Assurance of Metabolomics

von Bouhifd, Mounir, Beger, Richard, Flynn, Thomas, Guo, Lining, Harris, Georgina, Hogberg, Helena, Kaddurah-Daouk, Rima, Kamp, Hennicke, Kleensang, Andre, Maertens, Alexandra, Odwin-DaCosta, Shelly, Pamies, David, Robertson, Donald, Smirnova, Lena, Sun, Jinchun, Zhao, Liang, Hartung, Thomas
Veröffentlicht in ALTEX (2015)

A Human Brain Microphysiological System Derived from Induced Pluripotent Stem Cells to Study Neurological Diseases and Toxicity

von Pamies, David, Barrera, Paula, Block, Katharina, Makri, Georgia, Kumar, Anupama, Wiersma, Daphne, Smirnova, Lena, Zhang, Ce, Bressler, Joseph, Christian, Kimberly M., Harris, Georgina, Ming, Guo-li, Berlinicke, Cindy J., Kyro, Kelly, Song, Hongjun, Pardo, Carlos A., Hartung, Thomas, Hogberg, Helena T.
Veröffentlicht in ALTEX (2016)

Alzheimer disease research in the 21(st) century: past and current failures, new perspectives and funding priorities

von Pistollato, Francesca, Ohayon, Elan L., Lam, Ann, Langley, Gillian R., Novak, Thomas J., Pamies, David, Perry, George, Trushina, Eugenia, Williams, Robin S.B., Roher, Alex E., Hartung, Thomas, Harnad, Stevan, Barnard, Neal, Morris, Martha Clare, Lai, Mei-Chun, Merkley, Ryan, Chandrasekera, P. Charukeshi
Veröffentlicht in Oncotarget (2016)

t(4) report: Toward Good Read-Across Practice (GRAP) Guidance

von Ball, Nicholas, Cronin, Mark T. D., Shen, Jie, Blackburn, Karen, Booth, Ewan D., Bouhifd, Mounir, Donley, Elizabeth, Egnash, Laura, Hastings, Charles, Juberg, Daland R., Kleensang, Andre, Kleinstreuer, Nicole, Kroese, E. Dinant, Lee, Adam C., Luechtefeld, Thomas, Maertens, Alexandra, Marty, Sue, Naciff, Jorge M., Palmer, Jessica, Pamies, David, Penman, Mike, Richarz, Andrea-Nicole, Russo, Daniel P., Stuard, Sharon B., Patlewicz, Grace, van Ravenzwaay, Bennard, Wu, Shengde, Zhu, Hao, Hartung, Thomas
Veröffentlicht in ALTEX (2016)