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Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheres

Human induced pluripotent stem cells (iPSCs), together with 21st century cell culture methods, have the potential to better model human physiology with applications in toxicology, disease modeling, and the study of host-pathogen interactions. Several models of the human brain have been developed rec...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Abreu, Celina Monteiro, Gama, Lucio, Krasemann, Susanne, Chesnut, Megan, Odwin-Dacosta, Shelly, Hogberg, Helena T., Hartung, Thomas, Pamies, David
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296317/
https://ncbi.nlm.nih.gov/pubmed/30619100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02766
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