Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model

Selective serotonin reuptake inhibitors (SSRIs) are frequently used to treat depression during pregnancy. Various concerns have been raised about the possible effects of these drugs on fetal development. Current developmental neurotoxicity (DNT) testing conducted in rodents is expensive, time-consum...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Zhong, Xiali, Harris, Georgina, Smirnova, Lena, Zufferey, Valentin, Sá, Rita de Cássia da Silveira e, Baldino Russo, Fabiele, Baleeiro Beltrao Braga, Patricia Cristina, Chesnut, Megan, Zurich, Marie-Gabrielle, Hogberg, Helena T., Hartung, Thomas, Pamies, David
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cellular Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047331/
https://ncbi.nlm.nih.gov/pubmed/32153365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00025
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