Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model

Selective serotonin reuptake inhibitors (SSRIs) are frequently used to treat depression during pregnancy. Various concerns have been raised about the possible effects of these drugs on fetal development. Current developmental neurotoxicity (DNT) testing conducted in rodents is expensive, time-consum...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Zhong, Xiali, Harris, Georgina, Smirnova, Lena, Zufferey, Valentin, Sá, Rita de Cássia da Silveira e, Baldino Russo, Fabiele, Baleeiro Beltrao Braga, Patricia Cristina, Chesnut, Megan, Zurich, Marie-Gabrielle, Hogberg, Helena T., Hartung, Thomas, Pamies, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Cellular Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7047331/
https://ncbi.nlm.nih.gov/pubmed/32153365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00025
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