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3D differentiation of LUHMES cell line to study recovery and delayed neurotoxic effects

Current neurotoxicity testing and study of molecular mechanisms in neurodegeneration, in vitro, usually focuses on acute exposures to compounds. 3D LUHMES allow long-term treatment or pulse exposure in combination with compound wash-out to study delayed neurotoxic effects as well as recovery and neu...

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Detalhes bibliográficos
Publicado no:Curr Protoc Toxicol
Main Authors: Harris, Georgina, Hogberg, Helena, Hartung, Thomas, Smirnova, Lena
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674809/
https://ncbi.nlm.nih.gov/pubmed/28777440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cptx.29
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