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3D differentiation of LUHMES cell line to study recovery and delayed neurotoxic effects

Current neurotoxicity testing and study of molecular mechanisms in neurodegeneration, in vitro, usually focuses on acute exposures to compounds. 3D LUHMES allow long-term treatment or pulse exposure in combination with compound wash-out to study delayed neurotoxic effects as well as recovery and neu...

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Dades bibliogràfiques
Publicat a:Curr Protoc Toxicol
Autors principals: Harris, Georgina, Hogberg, Helena, Hartung, Thomas, Smirnova, Lena
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674809/
https://ncbi.nlm.nih.gov/pubmed/28777440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cptx.29
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