A Human Brain Microphysiological System Derived from Induced Pluripotent Stem Cells to Study Neurological Diseases and Toxicity

Human in vitro models of brain neurophysiology are needed to investigate molecular and cellular mechanisms associated with neurological disorders and neurotoxicity. We have developed a reproducible iPSC-derived human 3D brain microphysiological system (BMPS), comprised of differentiated mature neuro...

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Bibliografiske detaljer
Udgivet i:ALTEX
Main Authors: Pamies, David, Barrera, Paula, Block, Katharina, Makri, Georgia, Kumar, Anupama, Wiersma, Daphne, Smirnova, Lena, Zhang, Ce, Bressler, Joseph, Christian, Kimberly M., Harris, Georgina, Ming, Guo-li, Berlinicke, Cindy J., Kyro, Kelly, Song, Hongjun, Pardo, Carlos A., Hartung, Thomas, Hogberg, Helena T.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047513/
https://ncbi.nlm.nih.gov/pubmed/27883356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14573/altex.1609122
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