A Human Brain Microphysiological System Derived from Induced Pluripotent Stem Cells to Study Neurological Diseases and Toxicity

Human in vitro models of brain neurophysiology are needed to investigate molecular and cellular mechanisms associated with neurological disorders and neurotoxicity. We have developed a reproducible iPSC-derived human 3D brain microphysiological system (BMPS), comprised of differentiated mature neuro...

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Detalhes bibliográficos
Publicado no:ALTEX
Main Authors: Pamies, David, Barrera, Paula, Block, Katharina, Makri, Georgia, Kumar, Anupama, Wiersma, Daphne, Smirnova, Lena, Zhang, Ce, Bressler, Joseph, Christian, Kimberly M., Harris, Georgina, Ming, Guo-li, Berlinicke, Cindy J., Kyro, Kelly, Song, Hongjun, Pardo, Carlos A., Hartung, Thomas, Hogberg, Helena T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047513/
https://ncbi.nlm.nih.gov/pubmed/27883356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14573/altex.1609122
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