Suitability of 3D human brain spheroid models to distinguish toxic effects of gold and poly-lactic acid nanoparticles to assess biocompatibility for brain drug delivery

BACKGROUND: The blood brain barrier (BBB) is the bottleneck of brain-targeted drug development. Due to their physico-chemical properties, nanoparticles (NP) can cross the BBB and accumulate in different areas of the central nervous system (CNS), thus are potential tools to carry drugs and treat brai...

詳細記述

保存先:
書誌詳細
出版年:Part Fibre Toxicol
主要な著者: Leite, Paulo Emílio Corrêa, Pereira, Mariana Rodrigues, Harris, Georgina, Pamies, David, dos Santos, Lisia Maria Gobbo, Granjeiro, José Mauro, Hogberg, Helena T., Hartung, Thomas, Smirnova, Lena
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545685/
https://ncbi.nlm.nih.gov/pubmed/31159811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-019-0307-3
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料