Functional analysis of four LDLR 5′UTR and promoter variants in patients with familial hypercholesterolaemia

Por Khamis, Amna, Palmen, Jutta, Lench, Nick, Taylor, Alison, Badmus, Ebele, Leigh, Sarah, Humphries, Steve E
Publicado no Eur J Hum Genet (2015)

Application of statistical and functional methodologies for the investigation of genetic determinants of coronary heart disease biomarkers: lipoprotein lipase genotype and plasma t...

Por Smith, Andrew J.P., Palmen, Jutta, Putt, Wendy, Talmud, Philippa J., Humphries, Steve E., Drenos, Fotios
Publicado em 2010

Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk

Por Drenos, Fotios, Talmud, Philippa J., Casas, Juan P., Smeeth, Liam, Palmen, Jutta, Humphries, Steve E., Hingorani, Aroon D.
Publicado em 2009

Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3

Por Oldoni, Federico, Palmen, Jutta, Giambartolomei, Claudia, Howard, Philip, Drenos, Fotios, Plagnol, Vincent, Humphries, Steve E., Talmud, Philippa J., Smith, Andrew J.P.
Publicado no Atherosclerosis (2016)

Demonstration of the Presence of the “Deleted” MIR122 Gene in HepG2 Cells

Por Hamad, Ibrahim A. Y., Fei, Yue, Kalea, Anastasia Z., Yin, Dan, Smith, Andrew J. P., Palmen, Jutta, Humphries, Steve E., Talmud, Philippa J., Walker, Ann P.
Publicado no PLoS One (2015)

Functional Analysis of Two PLA2G2A Variants Associated with Secretory Phospholipase A2-IIA Levels

Por Exeter, Holly J., Folkersen, Lasse, Palmen, Jutta, Franco-Cereceda, Anders, Cooper, Jackie A., Kalea, Anastasia Z., Hooft, Ferdinand van’t, Eriksson, Per, Humphries, Steve E., Talmud, Philippa J.
Publicado em 2012

Plasma heat shock protein 60 and cardiovascular disease risk: the role of psychosocial, genetic, and biological factors

Por Shamaei-Tousi, Alireza, Steptoe, Andrew, O'Donnell, Katie, Palmen, Jutta, Stephens, Jeffrey W., Hurel, Steven J., Marmot, Michael, Homer, Karen, D'Aiuto, Francesco, Coates, Anthony R.M., Humphries, Steve E., Henderson, Brian
Publicado em 2007

Use of Allele-Specific FAIRE to Determine Functional Regulatory Polymorphism Using Large-Scale Genotyping Arrays

Por Smith, Andrew J. P., Howard, Philip, Shah, Sonia, Eriksson, Per, Stender, Stefan, Giambartolomei, Claudia, Folkersen, Lasse, Tybjærg-Hansen, Anne, Kumari, Meena, Palmen, Jutta, Hingorani, Aroon D., Talmud, Philippa J., Humphries, Steve E.
Publicado em 2012

Association of TERC and OBFC1 Haplotypes with Mean Leukocyte Telomere Length and Risk for Coronary Heart Disease

Por Maubaret, Cécilia G., Salpea, Klelia D., Romanoski, Casey E., Folkersen, Lasse, Cooper, Jackie A., Stephanou, Coralea, Wah Li, Ka, Palmen, Jutta, Hamsten, Anders, Neil, Andrew, Stephens, Jeffrey W., Lusis, Aldons J., Eriksson, Per, Talmud, Philippa J., Humphries, Steve E.
Publicado em 2013

Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies

Por Shah, Sonia, Casas, Juan P., Gaunt, Tom R., Cooper, Jackie, Drenos, Fotios, Zabaneh, Delilah, Swerdlow, Daniel I., Shah, Tina, Sofat, Reecha, Palmen, Jutta, Kumari, Meena, Kivimaki, Mika, Ebrahim, Shah, Smith, George Davey, Lawlor, Debbie A., Talmud, Philippa J., Whittaker, John, Day, Ian N.M., Hingorani, Aroon D., Humphries, Steve E.
Publicado em 2013

Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts

Por Zabaneh, Delilah, Kumari, Meena, Sandhu, Manj, Wareham, Nick, Wainwright, Nick, Papamarkou, Theodore, Hopewell, Jemma, Clarke, Robert, Li, KaWah, Palmen, Jutta, Talmud, Philippa J, Kronenberg, Florian, Lamina, Claudia, Summerer, Monika, Paulweber, Bernhard, Price, Jackie, Fowkes, Gerry, Drenos, Marlene Stewart Fotios, Shah, Sonia, Shah, Tina, Casas, Juan Pablo, Kivimaki, Mika, Whittaker, John, Hingorani, Aroon D, Humphries, Steve E
Publicado em 2011

PLA2G7 genotype, Lp-PLA2 activity and coronary heart disease risk in 10,494 cases and 15,624 controls of European ancestry

Por Casas, Juan P., Ninio, Ewa, Panayiotou, Andrie, Palmen, Jutta, Cooper, Jackie A, Ricketts, Sally L, Sofat, Reecha, Nicolaides, Andrew N, Corsetti, James P, Fowkes, F Gerry R, Tzoulaki, Ioanna, Kumari, Meena, Brunner, Eric J, Kivimaki, Mika, Marmot, Michael G, Hoffmann, Michael M, Winkler, Karl, März, Winfred, Ye, Shu, Stirnadel, Heide A, MBBChir, Kay-Tee Khaw, Humphries, Steve E, Sandhu, Manjinder S, Hingorani, Aroon D, Talmud, Philippa J
Publicado em 2010

A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease

Por Holmes, Michael V., Frikke-Schmidt, Ruth, Melis, Daniela, Luben, Robert, Asselbergs, Folkert W., Boer, Jolanda M.A., Cooper, Jackie, Palmen, Jutta, Horvat, Pia, Engmann, Jorgen, Li, Ka-Wah, Onland-Moret, N. Charlotte, Hofker, Marten H., Kumari, Meena, Keating, Brendan J., Hubacek, Jaroslav A., Adamkova, Vera, Kubinova, Ruzena, Bobak, Martin, Khaw, Kay-Tee, Nordestgaard, Børge G., Wareham, Nick, Humphries, Steve E., Langenberg, Claudia, Tybjaerg-Hansen, Anne, Talmud, Philippa J.
Publicado no Atherosclerosis (2014)

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Por Talmud, Philippa J., Drenos, Fotios, Shah, Sonia, Shah, Tina, Palmen, Jutta, Verzilli, Claudio, Gaunt, Tom R., Pallas, Jacky, Lovering, Ruth, Li, Kawah, Casas, Juan Pablo, Sofat, Reecha, Kumari, Meena, Rodriguez, Santiago, Johnson, Toby, Newhouse, Stephen J., Dominiczak, Anna, Samani, Nilesh J., Caulfield, Mark, Sever, Peter, Stanton, Alice, Shields, Denis C., Padmanabhan, Sandosh, Melander, Olle, Hastie, Claire, Delles, Christian, Ebrahim, Shah, Marmot, Michael G., Smith, George Davey, Lawlor, Debbie A., Munroe, Patricia B., Day, Ian N., Kivimaki, Mika, Whittaker, John, Humphries, Steve E., Hingorani, Aroon D.
Publicado em 2009

A genome-wide association study identifies multiple loci for variation in human ear morphology

Por Adhikari, Kaustubh, Reales, Guillermo, Smith, Andrew J. P., Konka, Esra, Palmen, Jutta, Quinto-Sanchez, Mirsha, Acuña-Alonzo, Victor, Jaramillo, Claudia, Arias, William, Fuentes, Macarena, Pizarro, María, Barquera Lozano, Rodrigo, Macín Pérez, Gastón, Gómez-Valdés, Jorge, Villamil-Ramírez, Hugo, Hunemeier, Tábita, Ramallo, Virginia, Silva de Cerqueira, Caio C., Hurtado, Malena, Villegas, Valeria, Granja, Vanessa, Gallo, Carla, Poletti, Giovanni, Schuler-Faccini, Lavinia, Salzano, Francisco M., Bortolini, Maria- Cátira, Canizales-Quinteros, Samuel, Rothhammer, Francisco, Bedoya, Gabriel, Calderón, Rosario, Rosique, Javier, Cheeseman, Michael, Bhutta, Mahmood F., Humphries, Steve E., Gonzalez-José, Rolando, Headon, Denis, Balding, David, Ruiz-Linares, Andrés
Publicado no Nat Commun (2015)

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

Por Angelakopoulou, Aspasia, Shah, Tina, Sofat, Reecha, Shah, Sonia, Berry, Diane J., Cooper, Jackie, Palmen, Jutta, Tzoulaki, Ioanna, Wong, Andrew, Jefferis, Barbara J., Maniatis, Nikolas, Drenos, Fotios, Gigante, Bruna, Hardy, Rebecca, Laxton, Ross C., Leander, Karin, Motterle, Anna, Simpson, Iain A., Smeeth, Liam, Thomson, Andy, Verzilli, Claudio, Kuh, Diana, Ireland, Helen, Deanfield, John, Caulfield, Mark, Wallace, Chris, Samani, Nilesh, Munroe, Patricia B., Lathrop, Mark, Fowkes, F. Gerry R., Marmot, Michael, Whincup, Peter H., Whittaker, John C., de Faire, Ulf, Kivimaki, Mika, Kumari, Meena, Hypponen, Elina, Power, Chris, Humphries, Steve E., Talmud, Philippa J., Price, Jackie, Morris, Richard W., Ye, Shu, Casas, Juan P., Hingorani, Aroon D.
Publicado em 2012

Abdominal Aortic Aneurysm Is Associated with a Variant in Low-Density Lipoprotein Receptor-Related Protein 1

Por Bown, Matthew J., Jones, Gregory T., Harrison, Seamus C., Wright, Benjamin J., Bumpstead, Suzannah, Baas, Annette F., Gretarsdottir, Solveig, Badger, Stephen A., Bradley, Declan T., Burnand, Kevin, Child, Anne H., Clough, Rachel E., Cockerill, Gillian, Hafez, Hany, Scott, D. Julian A., Futers, Simon, Johnson, Anne, Sohrabi, Soroush, Smith, Alberto, Thompson, Matthew M., van Bockxmeer, Frank M., Waltham, Matthew, Matthiasson, Stefan E., Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Blankensteijn, Jan D., Teijink, Joep A.W., Wijmenga, Cisca, de Graaf, Jacqueline, Kiemeney, Lambertus A., Assimes, Themistocles L., McPherson, Ruth, Folkersen, Lasse, Franco-Cereceda, Anders, Palmen, Jutta, Smith, Andrew J., Sylvius, Nicolas, Wild, John B., Refstrup, Mette, Edkins, Sarah, Gwilliam, Rhian, Hunt, Sarah E., Potter, Simon, Lindholt, Jes S., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Hughes, Anne E., Golledge, Jonathan, Norman, Paul E., van Rij, Andre, Powell, Janet T., Eriksson, Per, Stefansson, Kari, Thompson, John R., Humphries, Steve E., Sayers, Robert D., Deloukas, Panos, Samani, Nilesh J.
Publicado em 2011

Blood Pressure Loci Identified with a Gene-Centric Array

Por Johnson, Toby, Gaunt, Tom R., Newhouse, Stephen J., Padmanabhan, Sandosh, Tomaszewski, Maciej, Kumari, Meena, Morris, Richard W., Tzoulaki, Ioanna, O'Brien, Eoin T., Poulter, Neil R., Sever, Peter, Shields, Denis C., Thom, Simon, Wannamethee, Sasiwarang G., Whincup, Peter H., Brown, Morris J., Connell, John M., Dobson, Richard J., Howard, Philip J., Mein, Charles A., Onipinla, Abiodun, Shaw-Hawkins, Sue, Zhang, Yun, Smith, George Davey, Day, Ian N.M., Lawlor, Debbie A., Goodall, Alison H., Fowkes, F. Gerald, Abecasis, Gonçalo R., Elliott, Paul, Gateva, Vesela, Braund, Peter S., Burton, Paul R., Nelson, Christopher P., Tobin, Martin D., van der Harst, Pim, Glorioso, Nicola, Neuvrith, Hani, Salvi, Erika, Staessen, Jan A., Stucchi, Andrea, Devos, Nabila, Jeunemaitre, Xavier, Plouin, Pierre-François, Tichet, Jean, Juhanson, Peeter, Org, Elin, Putku, Margus, Sõber, Siim, Veldre, Gudrun, Viigimaa, Margus, Levinsson, Anna, Rosengren, Annika, Thelle, Dag S., Hastie, Claire E., Hedner, Thomas, Lee, Wai K., Melander, Olle, Wahlstrand, Björn, Hardy, Rebecca, Wong, Andrew, Cooper, Jackie A., Palmen, Jutta, Chen, Li, Stewart, Alexandre F.R., Wells, George A., Westra, Harm-Jan, Wolfs, Marcel G.M., Clarke, Robert, Franzosi, Maria Grazia, Goel, Anuj, Hamsten, Anders, Lathrop, Mark, Peden, John F., Seedorf, Udo, Watkins, Hugh, Ouwehand, Willem H., Sambrook, Jennifer, Stephens, Jonathan, Casas, Juan-Pablo, Drenos, Fotios, Holmes, Michael V., Kivimaki, Mika, Shah, Sonia, Shah, Tina, Talmud, Philippa J., Whittaker, John, Wallace, Chris, Delles, Christian, Laan, Maris, Kuh, Diana, Humphries, Steve E., Nyberg, Fredrik, Cusi, Daniele, Roberts, Robert, Newton-Cheh, Christopher, Franke, Lude, Stanton, Alice V., Dominiczak, Anna F., Farrall, Martin, Hingorani, Aroon D., Samani, Nilesh J., Caulfield, Mark J., Munroe, Patricia B.
Publicado em 2011

Identification of seven loci affecting mean telomere length and their association with disease

Por Codd, Veryan, Nelson, Christopher P., Albrecht, Eva, Mangino, Massimo, Deelen, Joris, Buxton, Jessica L., Jan Hottenga, Jouke, Fischer, Krista, Esko, Tõnu, Surakka, Ida, Broer, Linda, Nyholt, Dale R., Mateo Leach, Irene, Salo, Perttu, Hägg, Sara, Matthews, Mary K., Palmen, Jutta, Norata, Giuseppe D., O’Reilly, Paul F., Saleheen, Danish, Amin, Najaf, Balmforth, Anthony J., Beekman, Marian, de Boer, Rudolf A., Böhringer, Stefan, Braund, Peter S., Burton, Paul R., de Craen, Anton J. M., Denniff, Matthew, Dong, Yanbin, Douroudis, Konstantinos, Dubinina, Elena, Eriksson, Johan G., Garlaschelli, Katia, Guo, Dehuang, Hartikainen, Anna-Liisa, Henders, Anjali K., Houwing-Duistermaat, Jeanine J., Kananen, Laura, Karssen, Lennart C., Kettunen, Johannes, Klopp, Norman, Lagou, Vasiliki, van Leeuwen, Elisabeth M., Madden, Pamela A., Mägi, Reedik, Magnusson, Patrik K.E., Männistö, Satu, McCarthy, Mark I., Medland, Sarah E., Mihailov, Evelin, Montgomery, Grant W., Oostra, Ben A., Palotie, Aarno, Peters, Annette, Pollard, Helen, Pouta, Anneli, Prokopenko, Inga, Ripatti, Samuli, Salomaa, Veikko, Suchiman, H. Eka D., Valdes, Ana M., Verweij, Niek, Viñuela, Ana, Wang, Xiaoling, Wichmann, H.-Erich, Widen, Elisabeth, Willemsen, Gonneke, Wright, Margaret J., Xia, Kai, Xiao, Xiangjun, van Veldhuisen, Dirk J., Catapano, Alberico L., Tobin, Martin D., Hall, Alistair S., Blakemore, Alexandra I.F., van Gilst, Wiek H., Zhu, Haidong, Erdmann, Jeanette, Reilly, Muredach P., Kathiresan, Sekar, Schunkert, Heribert, Talmud, Philippa J., Pedersen, Nancy L., Perola, Markus, Ouwehand, Willem, Kaprio, Jaakko, Martin, Nicholas G., van Duijn, Cornelia M., Hovatta, Iiris, Gieger, Christian, Metspalu, Andres, Boomsma, Dorret I., Jarvelin, Marjo-Riitta, Slagboom, P. Eline, Thompson, John R., Spector, Tim D., van der Harst, Pim, Samani, Nilesh J.
Publicado em 2013

Secretory Phospholipase A(2)-IIA and Cardiovascular Disease: A Mendelian Randomization Study

Por Holmes, Michael V., Simon, Tabassome, Exeter, Holly J., Folkersen, Lasse, Asselbergs, Folkert W., Guardiola, Montse, Cooper, Jackie A., Palmen, Jutta, Hubacek, Jaroslav A., Carruthers, Kathryn F., Horne, Benjamin D., Brunisholz, Kimberly D., Mega, Jessica L., van Iperen, Erik P.A., Li, Mingyao, Leusink, Maarten, Trompet, Stella, Verschuren, Jeffrey J.W., Hovingh, G. Kees, Dehghan, Abbas, Nelson, Christopher P., Kotti, Salma, Danchin, Nicolas, Scholz, Markus, Haase, Christiane L., Rothenbacher, Dietrich, Swerdlow, Daniel I., Kuchenbaecker, Karoline B., Staines-Urias, Eleonora, Goel, Anuj, van 't Hooft, Ferdinand, Gertow, Karl, de Faire, Ulf, Panayiotou, Andrie G., Tremoli, Elena, Baldassarre, Damiano, Veglia, Fabrizio, Holdt, Lesca M., Beutner, Frank, Gansevoort, Ron T., Navis, Gerjan J., Mateo Leach, Irene, Breitling, Lutz P., Brenner, Hermann, Thiery, Joachim, Dallmeier, Dhayana, Franco-Cereceda, Anders, Boer, Jolanda M.A., Stephens, Jeffrey W., Hofker, Marten H., Tedgui, Alain, Hofman, Albert, Uitterlinden, André G., Adamkova, Vera, Pitha, Jan, Onland-Moret, N. Charlotte, Cramer, Maarten J., Nathoe, Hendrik M., Spiering, Wilko, Klungel, Olaf H., Kumari, Meena, Whincup, Peter H., Morrow, David A., Braund, Peter S., Hall, Alistair S., Olsson, Anders G., Doevendans, Pieter A., Trip, Mieke D., Tobin, Martin D., Hamsten, Anders, Watkins, Hugh, Koenig, Wolfgang, Nicolaides, Andrew N., Teupser, Daniel, Day, Ian N.M., Carlquist, John F., Gaunt, Tom R., Ford, Ian, Sattar, Naveed, Tsimikas, Sotirios, Schwartz, Gregory G., Lawlor, Debbie A., Morris, Richard W., Sandhu, Manjinder S., Poledne, Rudolf, Maitland-van der Zee, Anke H., Khaw, Kay-Tee, Keating, Brendan J., van der Harst, Pim, Price, Jackie F., Mehta, Shamir R., Yusuf, Salim, Witteman, Jaqueline C.M., Franco, Oscar H., Jukema, J. Wouter, de Knijff, Peter, Tybjaerg-Hansen, Anne, Rader, Daniel J., Farrall, Martin, Samani, Nilesh J., Kivimaki, Mika, Fox, Keith A.A., Humphries, Steve E., Anderson, Jeffrey L., Boekholdt, S. Matthijs, Palmer, Tom M., Eriksson, Per, Paré, Guillaume, Hingorani, Aroon D., Sabatine, Marc S., Mallat, Ziad, Casas, Juan P., Talmud, Philippa J.
Publicado em 2013