Post-GWAS methodologies for localisation of functional non-coding variants: ANGPTL3

Genome-wide association studies have confirmed the involvement of non-coding angiopoietin-like 3 (ANGPTL3) gene variants with coronary artery disease, levels of low-density lipoprotein cholesterol (LDL-C), triglycerides and ANGPTL3 mRNA transcript. Extensive linkage disequilibrium at the locus, howe...

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Detalhes bibliográficos
Publicado no:Atherosclerosis
Main Authors: Oldoni, Federico, Palmen, Jutta, Giambartolomei, Claudia, Howard, Philip, Drenos, Fotios, Plagnol, Vincent, Humphries, Steve E., Talmud, Philippa J., Smith, Andrew J.P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773290/
https://ncbi.nlm.nih.gov/pubmed/26800306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2015.12.009
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