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Association of TERC and OBFC1 Haplotypes with Mean Leukocyte Telomere Length and Risk for Coronary Heart Disease

OBJECTIVE: To replicate the associations of leukocyte telomere length (LTL) with variants at four loci and to investigate their associations with coronary heart disease (CHD) and type II diabetes (T2D), in order to examine possible causal effects of telomere maintenance machinery on disease aetiolog...

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Main Authors: Maubaret, Cécilia G., Salpea, Klelia D., Romanoski, Casey E., Folkersen, Lasse, Cooper, Jackie A., Stephanou, Coralea, Wah Li, Ka, Palmen, Jutta, Hamsten, Anders, Neil, Andrew, Stephens, Jeffrey W., Lusis, Aldons J., Eriksson, Per, Talmud, Philippa J., Humphries, Steve E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861448/
https://ncbi.nlm.nih.gov/pubmed/24349443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083122
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