Immunotherapies in Non-Hodgkin’s Lymphoma

per Bezombes, Christine, Pérez-Galán, Patricia
Publicat a Cancers (Basel) (2021)

Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic era

per Pérez-Galán, Patricia, Dreyling, Martin, Wiestner, Adrian
Publicat 2011

Follicular Lymphoma Microenvironment: An Intricate Network Ready for Therapeutic Intervention

per Dobaño-López, Cèlia, Araujo-Ayala, Ferran, Serrat, Neus, Valero, Juan G., Pérez-Galán, Patricia
Publicat a Cancers (Basel) (2021)

Modular chiral gold(i) phosphite complexes

per Delpont, Nicolas, Escofet, Imma, Pérez-Galán, Patricia, Spiegl, Dirk, Raducan, Mihai, Bour, Christophe, Sinisi, Riccardo, Echavarren, Antonio M.
Publicat a Catal Sci Technol (2013)

ON 01910.Na is selectively cytotoxic for Chronic Lymphocytic Leukemia cells through a dual mechanism of action involving PI3K/AKT inhibition and induction of oxidative stress

per Chapman, Colby M., Sun, Xiameng, Roschewski, Mark, Aue, Georg, Farooqui, Mohamed, Stennett, Lawrence, Gibellini, Federica, Arthur, Diane, Pérez-Galán, Patricia, Wiestner, Adrian
Publicat 2012

ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

per Wang, Qiuyan, Mora-Jensen, Helena, Weniger, Marc A., Perez-Galan, Patricia, Wolford, Chris, Hai, Tsonwin, Ron, David, Chen, Weiping, Trenkle, William, Wiestner, Adrian, Ye, Yihong
Publicat 2009

The phosphatidylinositol-3-kinase inhibitor NVP-BKM120 overcomes resistance signals derived from microenvironment by regulating the Akt/FoxO3a/Bim axis in chronic lymphocytic leuke...

per Rosich, Laia, Saborit-Villarroya, Ifigènia, López-Guerra, Mónica, Xargay-Torrent, Sílvia, Montraveta, Arnau, Aymerich, Marta, Villamor, Neus, Campo, Elias, Pérez-Galán, Patricia, Roué, Gaël, Colomer, Dolors
Publicat 2013

Dual PI3K/mTOR inhibition is required to effectively impair microenvironment survival signals in mantle cell lymphoma

per Rosich, Laia, Montraveta, Arnau, Xargay-Torrent, Sílvia, López-Guerra, Mónica, Roldán, Jocabed, Aymerich, Marta, Salaverria, Itziar, Beà, Sílvia, Campo, Elías, Pérez-Galán, Patricia, Roué, Gaël, Colomer, Dolors
Publicat 2014

The BET bromodomain inhibitor CPI203 improves lenalidomide and dexamethasone activity in in vitro and in vivo models of multiple myeloma by blockade of Ikaros and MYC signaling

per Díaz, Tania, Rodríguez, Vanina, Lozano, Ester, Mena, Mari-Pau, Calderón, Marcos, Rosiñol, Laura, Martínez, Antonio, Tovar, Natalia, Pérez-Galán, Patricia, Bladé, Joan, Roué, Gaël, de Larrea, Carlos Fernández
Publicat a Haematologica (2017)

Synergistic anti-tumor activity of acadesine (AICAR) in combination with the anti-CD20 monoclonal antibody rituximab in in vivo and in vitro models of mantle cell lymphoma

per Montraveta, Arnau, Xargay-Torrent, Sílvia, López-Guerra, Mónica, Rosich, Laia, Pérez-Galán, Patricia, Salaverria, Itziar, Beà, Silvia, Kalko, Susana G., de Frias, Mercè, Campàs, Clara, Roué, Gaël, Colomer, Dolors
Publicat 2014

Treatment-induced oxidative stress and cellular antioxidant capacity determine response to bortezomib in mantle cell lymphoma

per Weniger, Marc A., Rizzatti, Edgar G., Perez-Galan, Patricia, Liu, Delong, Wang, Qiuyan, Munson, Peter J., Raghavachari, Nalini, White, Therese, Tweito, Megan M., Dunleavy, Kieron, Ye, Yihong, Wilson, Wyndham H., Wiestner, Adrian
Publicat 2011

Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia

per Gimenez, Neus, Tripathi, Rupal, Giró, Ariadna, Rosich, Laia, López-Guerra, Mònica, López-Oreja, Irene, Playa-Albinyana, Heribert, Arenas, Fabian, Mas, José Manuel, Pérez-Galán, Patricia, Delgado, Julio, Campo, Elias, Farrés, Judith, Colomer, Dolors
Publicat a Sci Rep (2020)

The Bruton tyrosine kinase inhibitor CC-292 shows activity in mantle cell lymphoma and synergizes with lenalidomide and NIK inhibitors depending on nuclear factor-κB mutational sta...

per Vidal-Crespo, Anna, Rodriguez, Vanina, Matas-Cespedes, Alba, Lee, Eriong, Rivas-Delgado, Alfredo, Giné, Eva, Navarro, Alba, Beà, Sílvia, Campo, Elias, López-Guillermo, Armando, Lopez-Guerra, Monica, Roué, Gaël, Colomer, Dolors, Pérez-Galán, Patricia
Publicat a Haematologica (2017)

Modeling Tumor-Host Interactions of Chronic Lymphocytic Leukemia in Xenografted Mice to Study Tumor Biology and Evaluate Targeted Therapy

per Herman, Sarah E. M., Sun, Xiameng, McAuley, Erin M., Hsieh, Matthew M., Pittaluga, Stefania, Raffeld, Mark, Liu, Delong, Keyvanfar, Keyvan, Chapman, Colby M., Chen, Jichun, Buggy, Joseph J., Aue, Georg, Tisdale, John F., Pérez-Galán, Patricia, Wiestner, Adrian
Publicat 2013

Boosting γδ T cell-mediated antibody-dependent cellular cytotoxicity by PD-1 blockade in follicular lymphoma

per Rossi, Cédric, Gravelle, Pauline, Decaup, Emilie, Bordenave, Julie, Poupot, Mary, Tosolini, Marie, Franchini, Don-Marc, Laurent, Camille, Morin, Renaud, Lagarde, Jean-Michel, Ysebaert, Loïc, Ligat, Laetitia, Jean, Christine, Savina, Ariel, Klein, Christian, Céspedes, Alba Matas, Perez-Galan, Patricia, Fournié, Jean-Jacques, Bezombes, Christine
Publicat a Oncoimmunology (2018)

CD69 expression potentially predicts response to bendamustine and its modulation by ibrutinib or idelalisib enhances cytotoxic effect in chronic lymphocytic leukemia

per Montraveta, Arnau, Lee-Vergés, Eriong, Roldán, Jocabed, Jiménez, Laura, Cabezas, Sandra, Clot, Guillem, Pinyol, Magda, Xargay-Torrent, Sílvia, Rosich, Laia, Arimany-Nardí, Cristina, Aymerich, Marta, Villamor, Neus, López-Guillermo, Armando, Pérez-Galán, Patricia, Roué, Gaël, Pastor-Anglada, Marçal, Campo, Elías, López-Guerra, Mónica, Colomer, Dolors
Publicat a Oncotarget (2015)

The human CD38 monoclonal antibody daratumumab shows anti-tumor activity and hampers leukemia-microenvironment interactions in chronic lymphocytic leukemia

per Matas-Céspedes, Alba, Vidal-Crespo, Anna, Rodriguez, Vanina, Villamor, Neus, Delgado, Julio, Giné, Eva, Roca-Ho, Heleia, Menéndez, Pablo, Campo, Elías, López-Guillermo, Armando, Colomer, Dolors, Roué, Gaël, Wiestner, Adrian, Parren, Paul W.H.I., Doshi, Parul, van Bueren, Jeroen Lammerts, Pérez-Galán, Patricia
Publicat a Clin Cancer Res (2016)

Daratumumab displays in vitro and in vivo anti-tumor activity in models of B-cell non-Hodgkin lymphoma and improves responses to standard chemo-immunotherapy regimens

per Vidal-Crespo, Anna, Matas-Céspedes, Alba, Rodriguez, Vanina, Rossi, Cédric, Valero, Juan G., Serrat, Neus, Sanjuan-Pla, Alejandra, Menéndez, Pablo, Roué, Gaël, López-Guillermo, Armando, Giné, Eva, Campo, Elías, Colomer, Dolors, Bezombes, Christine, van Bueren, Jeroen Lammerts, Chiu, Christopher, Doshi, Parul, Pérez-Galán, Patricia
Publicat a Haematologica (2020)

3D Model Characterization by 2D and 3D Imaging in t(14;18)-Positive B-NHL: Perspectives for In Vitro Drug Screens in Follicular Lymphoma

per Gava, Fabien, Faria, Carla, Gravelle, Pauline, Valero, Juan G., Dobaño-López, Cèlia, Morin, Renaud, Norlund, Marine, Gomes, Aurélie, Lagarde, Jean-Michel, Rossi, Cédric, Bordenave, Julie, Pieruccioni, Laetitia, Rouquette, Jacques, Matas-Céspedes, Alba, Fournié, Jean-Jacques, Ysebaert, Loïc, Laurent, Camille, Pérez-Galán, Patricia, Bezombes, Christine
Publicat a Cancers (Basel) (2021)

Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation

per Pérez-Galán, Patricia, Mora-Jensen, Helena, Weniger, Marc A., Shaffer, Arthur L., Rizzatti, Edgar G., Chapman, Colby M., Mo, Clifton C., Stennett, Lawrence S., Rader, Christoph, Liu, Poching, Raghavachari, Nalini, Stetler-Stevenson, Maryalice, Yuan, Constance, Pittaluga, Stefania, Maric, Irina, Dunleavy, Kieron M., Wilson, Wyndham H., Staudt, Louis M., Wiestner, Adrian
Publicat 2011