CD69 expression potentially predicts response to bendamustine and its modulation by ibrutinib or idelalisib enhances cytotoxic effect in chronic lymphocytic leukemia

Clinical responses to bendamustine in chronic lymphocytic leukemia (CLL) are highly heterogeneous and no specific markers to predict sensitivity to this drug have been reported. In order to identify biomarkers of response, we analyzed the in vitro activity of bendamustine and the gene expression pro...

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發表在:Oncotarget
Main Authors: Montraveta, Arnau, Lee-Vergés, Eriong, Roldán, Jocabed, Jiménez, Laura, Cabezas, Sandra, Clot, Guillem, Pinyol, Magda, Xargay-Torrent, Sílvia, Rosich, Laia, Arimany-Nardí, Cristina, Aymerich, Marta, Villamor, Neus, López-Guillermo, Armando, Pérez-Galán, Patricia, Roué, Gaël, Pastor-Anglada, Marçal, Campo, Elías, López-Guerra, Mónica, Colomer, Dolors
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2015
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868702/
https://ncbi.nlm.nih.gov/pubmed/26701728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6685
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