The splicing modulator sudemycin induces a specific antitumor response and cooperates with ibrutinib in chronic lymphocytic leukemia

Mutations or deregulated expression of the components of the spliceosome can influence the splicing pattern of several genes and contribute to the development of tumors. In this context, we report that the spliceosome modulator sudemycin induces selective cytotoxicity in primary chronic lymphocytic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Xargay-Torrent, Sílvia, López-Guerra, Mónica, Rosich, Laia, Montraveta, Arnau, Roldán, Jocabed, Rodríguez, Vanina, Villamor, Neus, Aymerich, Marta, Lagisetti, Chandraiah, Webb, Thomas R., López-Otín, Carlos, Campo, Elias, Colomer, Dolors
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673195/
https://ncbi.nlm.nih.gov/pubmed/26068951
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados