Systemic Administration of Sclerostin Antibody Enhances Bone Repair in a Critical-Sized Femoral Defect in a Rat Model

Por Virk, Mandeep S., Alaee, Farhang, Tang, Hezhen, Ominsky, Michael S., Ke, Hua Zhu, Lieberman, Jay R.
Publicado em 2013

Sclerostin Antibody Treatment Enhances Rotator Cuff Tendon-to-Bone Healing in an Animal Model

Por Shah, Shivam A., Kormpakis, Ioannis, Havlioglu, Necat, Ominsky, Michael S., Galatz, Leesa M., Thomopoulos, Stavros
Publicado no J Bone Joint Surg Am (2017)

Differential time-dependent transcriptional changes in the osteoblast lineage in cortical bone associated with sclerostin antibody treatment in ovariectomized rats

Por Taylor, Scott, Hu, Rong, Pacheco, Efrain, Locher, Kathrin, Pyrah, Ian, Ominsky, Michael S., Boyce, Rogely Waite
Publicado no Bone Rep (2018)

Osteoprotegerin Abrogated Cortical Porosity and Bone Marrow Fibrosis in a Mouse Model of Constitutive Activation of the PTH/PTHrP Receptor

Por Ohishi, Masanobu, Chiusaroli, Riccardo, Ominsky, Michael, Asuncion, Frank, Thomas, Clare, Khatri, Richa, Kostenuik, Paul, Schipani, Ernestina
Publicado em 2009

Sclerostin Antibody Improves Skeletal Parameters in a Brtl/+ Mouse Model of Osteogenesis Imperfecta

Por Sinder, Benjamin P., Eddy, Mary M., Ominsky, Michael S, Caird, Michelle S., Marini, Joan C., Kozloff, Kenneth M.
Publicado em 2013

Rapidly Growing Brtl/+ Mouse Model of Osteogenesis Imperfecta Improves Bone Mass and Strength with Sclerostin Antibody Treatment

Por Sinder, Benjamin P., Salemi, Joseph D., Ominsky, Michael S., Caird, Michelle S., Marini, Joan C., Kozloff, Kenneth M.
Publicado no Bone (2014)

Decreased osteoprogenitor proliferation precedes attenuation of cancellous bone formation in ovariectomized rats treated with sclerostin antibody

Por Boyce, Rogely Waite, Brown, Danielle, Felx, Melanie, Mellal, Nacera, Locher, Kathrin, Pyrah, Ian, Ominsky, Michael S., Taylor, Scott
Publicado no Bone Rep (2018)

Are Osteoclasts Needed for the Bone Anabolic Response to Parathyroid Hormone?: A STUDY OF INTERMITTENT PARATHYROID HORMONE WITH DENOSUMAB OR ALENDRONATE IN KNOCK-IN MICE EXPRESSING...

Por Pierroz, Dominique D., Bonnet, Nicolas, Baldock, Paul A., Ominsky, Michael S., Stolina, Marina, Kostenuik, Paul J., Ferrari, Serge L.
Publicado em 2010

Adult Brtl/+ Mouse Model of Osteogenesis Imperfecta Demonstrates Anabolic Response to Sclerostin Antibody Treatment with Increased Bone Mass and Strength

Por Sinder, Benjamin P., White, Logan E., Salemi, Joseph D., Ominsky, Michael S., Caird, Michelle S., Marini, Joan C., Kozloff, Kenneth M.
Publicado no Osteoporos Int (2014)

Sclerostin antibody administration converts bone lining cells into active osteoblasts

Por Kim, Sang Wan, Lu, Yanhui, Williams, Elizabeth A., Lai, Forest, Lee, Ji Yeon, Enishi, Tetsuya, Balani, Deepak H., Ominsky, Michael S., Ke, Hua Zhu, Kronenberg, Henry M., Wein, Marc N.
Publicado no J Bone Miner Res (2017)

Sclerostin antibody treatment improves the bone phenotype of Crtap(−/−) mice, a model of recessive Osteogenesis Imperfecta

Por Grafe, Ingo, Alexander, Stefanie, Yang, Tao, Lietman, Caressa, Homan, Erica P, Munivez, Elda, Chen, Yuqing, Jiang, Ming Ming, Bertin, Terry, Dawson, Brian, Asuncion, Franklin, Ke, Hua Zhu, Ominsky, Michael S, Lee, Brendan
Publicado no J Bone Miner Res (2016)

A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair

Por Florio, Monica, Gunasekaran, Kannan, Stolina, Marina, Li, Xiaodong, Liu, Ling, Tipton, Barbara, Salimi-Moosavi, Hossein, Asuncion, Franklin J., Li, Chaoyang, Sun, Banghua, Tan, Hong Lin, Zhang, Li, Han, Chun-Ya, Case, Ryan, Duguay, Amy N., Grisanti, Mario, Stevens, Jennitte, Pretorius, James K., Pacheco, Efrain, Jones, Heidi, Chen, Qing, Soriano, Brian D., Wen, Jie, Heron, Brenda, Jacobsen, Frederick W., Brisan, Emil, Richards, William G., Ke, Hua Zhu, Ominsky, Michael S.
Publicado no Nat Commun (2016)