Osteoprotegerin Abrogated Cortical Porosity and Bone Marrow Fibrosis in a Mouse Model of Constitutive Activation of the PTH/PTHrP Receptor

Intracortical porosities and marrow fibrosis are hallmarks of hyperparathyroidism and are present in bones of transgenic mice expressing constitutively active parathyroid hormone/parathyroid hormone-related protein receptors (PPR*Tg). Cortical porosity is the result of osteoclast activity; however,...

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Main Authors: Ohishi, Masanobu, Chiusaroli, Riccardo, Ominsky, Michael, Asuncion, Frank, Thomas, Clare, Khatri, Richa, Kostenuik, Paul, Schipani, Ernestina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684181/
https://ncbi.nlm.nih.gov/pubmed/19389927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.081026
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