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Rapidly Growing Brtl/+ Mouse Model of Osteogenesis Imperfecta Improves Bone Mass and Strength with Sclerostin Antibody Treatment

Osteogenesis imperfecta (OI) is a heritable collagen-related bone dysplasia, characterized by brittle bones with increased fracture risk that presents most severely in children. Anti-resorptive bisphosphonates are frequently used to treat pediatric OI and controlled clinical trials have shown bispho...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Sinder, Benjamin P., Salemi, Joseph D., Ominsky, Michael S., Caird, Michelle S., Marini, Joan C., Kozloff, Kenneth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274252/
https://ncbi.nlm.nih.gov/pubmed/25445450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.10.012
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