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Single Dose of Bisphosphonate Preserves Gains in Bone Mass Following Cessation of Sclerostin Antibody in Brtl/+ Osteogenesis Imperfecta Model
Sclerostin antibody has demonstrated a bone-forming effect in pre-clinical models of osteogenesis imperfecta, where mutations in collagen or collagen-associated proteins often result in high bone fragility in pediatric patients. Cessation studies in osteoporotic patients have demonstrated that scler...
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| Udgivet i: | Bone |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5077648/ https://ncbi.nlm.nih.gov/pubmed/27641475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.09.013 |
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