Highly efficient genome editing for single-base substitutions using optimized ssODNs with Cas9-RNPs

par Okamoto, Sachiko, Amaishi, Yasunori, Maki, Izumi, Enoki, Tatsuji, Mineno, Junichi
Publié dans Sci Rep (2019)

Tumor-specific donor lymphocyte infusion therapy with allogeneic T cells utilizing novel retrovirus vector silencing endogenous TCR expression

par Ikeda, Hiroaki, Ueno, Hiroaki, Kawamura, Ayumi, Imai, Naoko, Okamoto, Sachiko, Mineno, Junichi, Takesako, Kazutoh, Shiku, Hiroshi
Publié dans J Immunother Cancer (2014)

A Functionally Superior Second-Generation Vector Expressing an Aurora Kinase-A-Specific T-Cell Receptor for Anti-Leukaemia Adoptive Immunotherapy

par Casey, Nicholas Paul, Fujiwara, Hiroshi, Tanimoto, Kazushi, Okamoto, Sachiko, Mineno, Junichi, Kuzushima, Kiyotaka, Shiku, Hiroshi, Yasukawa, Masaki
Publié dans PLoS One (2016)

A Promising Vector for TCR Gene Therapy: Differential Effect of siRNA, 2A Peptide, and Disulfide Bond on the Introduced TCR Expression

par Okamoto, Sachiko, Amaishi, Yasunori, Goto, Yumi, Ikeda, Hiroaki, Fujiwara, Hiroshi, Kuzushima, Kiyotaka, Yasukawa, Masaki, Shiku, Hiroshi, Mineno, Junichi
Publié 2012

Genetic engineering of T cells with receptors from NY-ESO-1-specific tumor-recognizing CD4+ T cell as a novel approach for adoptive T cell therapy

par Matsuzaki, Junko, Tsuji, Takemasa, Luescher, Immanuel, Shiku, Hiroshi, Mineno, Junichi, Okamoto, Sachiko, Old, Lloyd, Shrikant, Protul, Gnjatic, Sacha, Odunsi, Kunle
Publié dans J Immunother Cancer (2015)

Efficient tumor regression by adoptively transferred CEA-specific CAR-T cells associated with symptoms of mild cytokine release syndrome

par Wang, Linan, Ma, Ning, Okamoto, Sachiko, Amaishi, Yasunori, Sato, Eiichi, Seo, Naohiro, Mineno, Junichi, Takesako, Kazutoh, Kato, Takuma, Shiku, Hiroshi
Publié dans Oncoimmunology (2016)

The expression profile of microRNAs in mouse embryos

par Mineno, Junichi, Okamoto, Sachiko, Ando, Tatsuya, Sato, Masahiro, Chono, Hideto, Izu, Hiroyuki, Takayama, Masanori, Asada, Kiyozo, Mirochnitchenko, Oleg, Inouye, Masayori, Kato, Ikunoshin
Publié 2006

Adoptive transfer of genetically modified Wilms' tumor 1–specific T cells in a novel malignant skull base meningioma model

par Iwami, Kenichiro, Natsume, Atsushi, Ohno, Masasuke, Ikeda, Hiroaki, Mineno, Junichi, Nukaya, Ikuei, Okamoto, Sachiko, Fujiwara, Hiroshi, Yasukawa, Masaki, Shiku, Hiroshi, Wakabayashi, Toshihiko
Publié 2013

Direct tumor recognition by a human CD4(+) T-cell subset potently mediates tumor growth inhibition and orchestrates anti-tumor immune responses

par Matsuzaki, Junko, Tsuji, Takemasa, Luescher, Immanuel F., Shiku, Hiroshi, Mineno, Junichi, Okamoto, Sachiko, Old, Lloyd J., Shrikant, Protul, Gnjatic, Sacha, Odunsi, Kunle
Publié dans Sci Rep (2015)

Co-Introduced Functional CCR2 Potentiates In Vivo Anti-Lung Cancer Functionality Mediated by T Cells Double Gene-Modified to Express WT1-Specific T-Cell Receptor

par Asai, Hiroaki, Fujiwara, Hiroshi, An, Jun, Ochi, Toshiki, Miyazaki, Yukihiro, Nagai, Kozo, Okamoto, Sachiko, Mineno, Junichi, Kuzushima, Kiyotaka, Shiku, Hiroshi, Inoue, Hirofumi, Yasukawa, Masaki
Publié 2013

Adoptive transfer of genetically engineered WT1-specific cytotoxic T lymphocytes does not induce renal injury

par Asai, Hiroaki, Fujiwara, Hiroshi, Kitazawa, Sohei, Kobayashi, Naoto, Ochi, Toshiki, Miyazaki, Yukihiro, Ochi, Fumihiro, Akatsuka, Yoshiki, Okamoto, Sachiko, Mineno, Junichi, Kuzushima, Kiyotaka, Ikeda, Hiroaki, Shiku, Hiroshi, Yasukawa, Masaki
Publié 2014

Antitumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination

par Akahori, Yasushi, Wang, Linan, Yoneyama, Motohiro, Seo, Naohiro, Okumura, Satoshi, Miyahara, Yoshihiro, Amaishi, Yasunori, Okamoto, Sachiko, Mineno, Junichi, Ikeda, Hiroaki, Maki, Takehiro, Fujiwara, Hiroshi, Akatsuka, Yoshiki, Kato, Takuma, Shiku, Hiroshi
Publié dans Blood (2018)