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Adoptive transfer of genetically engineered WT1-specific cytotoxic T lymphocytes does not induce renal injury

Because WT1 is expressed in leukemia cells, the development of cancer immunotherapy targeting WT1 has been an attractive translational research topic. However, concern of this therapy still remains, since WT1 is abundantly expressed in renal glomerular podocytes. In the present study, we clearly sho...

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Main Authors: Asai, Hiroaki, Fujiwara, Hiroshi, Kitazawa, Sohei, Kobayashi, Naoto, Ochi, Toshiki, Miyazaki, Yukihiro, Ochi, Fumihiro, Akatsuka, Yoshiki, Okamoto, Sachiko, Mineno, Junichi, Kuzushima, Kiyotaka, Ikeda, Hiroaki, Shiku, Hiroshi, Yasukawa, Masaki
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892144/
https://ncbi.nlm.nih.gov/pubmed/24393438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-7-3
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