Highly efficient genome editing for single-base substitutions using optimized ssODNs with Cas9-RNPs

Por Okamoto, Sachiko, Amaishi, Yasunori, Maki, Izumi, Enoki, Tatsuji, Mineno, Junichi
Publicado no Sci Rep (2019)

Tumor-specific donor lymphocyte infusion therapy with allogeneic T cells utilizing novel retrovirus vector silencing endogenous TCR expression

Por Ikeda, Hiroaki, Ueno, Hiroaki, Kawamura, Ayumi, Imai, Naoko, Okamoto, Sachiko, Mineno, Junichi, Takesako, Kazutoh, Shiku, Hiroshi
Publicado no J Immunother Cancer (2014)

A Functionally Superior Second-Generation Vector Expressing an Aurora Kinase-A-Specific T-Cell Receptor for Anti-Leukaemia Adoptive Immunotherapy

Por Casey, Nicholas Paul, Fujiwara, Hiroshi, Tanimoto, Kazushi, Okamoto, Sachiko, Mineno, Junichi, Kuzushima, Kiyotaka, Shiku, Hiroshi, Yasukawa, Masaki
Publicado no PLoS One (2016)

A Promising Vector for TCR Gene Therapy: Differential Effect of siRNA, 2A Peptide, and Disulfide Bond on the Introduced TCR Expression

Por Okamoto, Sachiko, Amaishi, Yasunori, Goto, Yumi, Ikeda, Hiroaki, Fujiwara, Hiroshi, Kuzushima, Kiyotaka, Yasukawa, Masaki, Shiku, Hiroshi, Mineno, Junichi
Publicado em 2012

Genetic engineering of T cells with receptors from NY-ESO-1-specific tumor-recognizing CD4+ T cell as a novel approach for adoptive T cell therapy

Por Matsuzaki, Junko, Tsuji, Takemasa, Luescher, Immanuel, Shiku, Hiroshi, Mineno, Junichi, Okamoto, Sachiko, Old, Lloyd, Shrikant, Protul, Gnjatic, Sacha, Odunsi, Kunle
Publicado no J Immunother Cancer (2015)

Efficient tumor regression by adoptively transferred CEA-specific CAR-T cells associated with symptoms of mild cytokine release syndrome

Por Wang, Linan, Ma, Ning, Okamoto, Sachiko, Amaishi, Yasunori, Sato, Eiichi, Seo, Naohiro, Mineno, Junichi, Takesako, Kazutoh, Kato, Takuma, Shiku, Hiroshi
Publicado no Oncoimmunology (2016)

The expression profile of microRNAs in mouse embryos

Por Mineno, Junichi, Okamoto, Sachiko, Ando, Tatsuya, Sato, Masahiro, Chono, Hideto, Izu, Hiroyuki, Takayama, Masanori, Asada, Kiyozo, Mirochnitchenko, Oleg, Inouye, Masayori, Kato, Ikunoshin
Publicado em 2006

Adoptive transfer of genetically modified Wilms' tumor 1–specific T cells in a novel malignant skull base meningioma model

Por Iwami, Kenichiro, Natsume, Atsushi, Ohno, Masasuke, Ikeda, Hiroaki, Mineno, Junichi, Nukaya, Ikuei, Okamoto, Sachiko, Fujiwara, Hiroshi, Yasukawa, Masaki, Shiku, Hiroshi, Wakabayashi, Toshihiko
Publicado em 2013

Direct tumor recognition by a human CD4(+) T-cell subset potently mediates tumor growth inhibition and orchestrates anti-tumor immune responses

Por Matsuzaki, Junko, Tsuji, Takemasa, Luescher, Immanuel F., Shiku, Hiroshi, Mineno, Junichi, Okamoto, Sachiko, Old, Lloyd J., Shrikant, Protul, Gnjatic, Sacha, Odunsi, Kunle
Publicado no Sci Rep (2015)

Co-Introduced Functional CCR2 Potentiates In Vivo Anti-Lung Cancer Functionality Mediated by T Cells Double Gene-Modified to Express WT1-Specific T-Cell Receptor

Por Asai, Hiroaki, Fujiwara, Hiroshi, An, Jun, Ochi, Toshiki, Miyazaki, Yukihiro, Nagai, Kozo, Okamoto, Sachiko, Mineno, Junichi, Kuzushima, Kiyotaka, Shiku, Hiroshi, Inoue, Hirofumi, Yasukawa, Masaki
Publicado em 2013

Adoptive transfer of genetically engineered WT1-specific cytotoxic T lymphocytes does not induce renal injury

Por Asai, Hiroaki, Fujiwara, Hiroshi, Kitazawa, Sohei, Kobayashi, Naoto, Ochi, Toshiki, Miyazaki, Yukihiro, Ochi, Fumihiro, Akatsuka, Yoshiki, Okamoto, Sachiko, Mineno, Junichi, Kuzushima, Kiyotaka, Ikeda, Hiroaki, Shiku, Hiroshi, Yasukawa, Masaki
Publicado em 2014

Antitumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination

Por Akahori, Yasushi, Wang, Linan, Yoneyama, Motohiro, Seo, Naohiro, Okumura, Satoshi, Miyahara, Yoshihiro, Amaishi, Yasunori, Okamoto, Sachiko, Mineno, Junichi, Ikeda, Hiroaki, Maki, Takehiro, Fujiwara, Hiroshi, Akatsuka, Yoshiki, Kato, Takuma, Shiku, Hiroshi
Publicado no Blood (2018)