Antitumor activity of CAR-T cells targeting the intracellular oncoprotein WT1 can be enhanced by vaccination

The recent success of chimeric antigen receptor (CAR)-T cell therapy for treatment of hematologic malignancies supports further development of treatments for both liquid and solid tumors. However, expansion of CAR-T cell therapy is limited by the availability of surface antigens specific for the tum...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood
Prif Awduron: Akahori, Yasushi, Wang, Linan, Yoneyama, Motohiro, Seo, Naohiro, Okumura, Satoshi, Miyahara, Yoshihiro, Amaishi, Yasunori, Okamoto, Sachiko, Mineno, Junichi, Ikeda, Hiroaki, Maki, Takehiro, Fujiwara, Hiroshi, Akatsuka, Yoshiki, Kato, Takuma, Shiku, Hiroshi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2018
Pynciau:
Immunobiology and Immunotherapy
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148344/
https://ncbi.nlm.nih.gov/pubmed/30045840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-08-802926
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