Transcriptional dysregulation by aberrant enhancer activation and rewiring in cancer

Tekijä Okabe, Atsushi, Kaneda, Atsushi
Julkaisussa Cancer Sci (2021)

Identification and characterization of the binding sequences and target genes of p53 lacking the 1st transactivation domain

Tekijä Suzuki, Shiori, Tsutsumi, Shuichi, Chen, Yu, Ozeki, Chikako, Okabe, Atsushi, Kawase, Tatsuya, Aburatani, Hiroyuki, Ohki, Rieko
Julkaisussa Cancer Sci (2020)

Histone modification alteration coordinated with acquisition of promoter DNA methylation during Epstein-Barr virus infection

Tekijä Funata, Sayaka, Matsusaka, Keisuke, Yamanaka, Ryota, Yamamoto, Shogo, Okabe, Atsushi, Fukuyo, Masaki, Aburatani, Hiroyuki, Fukayama, Masashi, Kaneda, Atsushi
Julkaisussa Oncotarget (2017)

Regulation of tumour related genes by dynamic epigenetic alteration at enhancer regions in gastric epithelial cells infected by Epstein-Barr virus

Tekijä Okabe, Atsushi, Funata, Sayaka, Matsusaka, Keisuke, Namba, Hiroe, Fukuyo, Masaki, Rahmutulla, Bahityar, Oshima, Motohiko, Iwama, Atsushi, Fukayama, Masashi, Kaneda, Atsushi
Julkaisussa Sci Rep (2017)

RNAi-Mediated Knockdown Showing Impaired Cell Survival in Drosophila Wing Imaginal Disc

Tekijä Umemori, Makoto, Habara, Okiko, Iwata, Tatsunori, Maeda, Kousuke, Nishinoue, Kana, Okabe, Atsushi, Takemura, Masahiko, Takahashi, Kuniaki, Saigo, Kaoru, Ueda, Ryu, Adachi-Yamada, Takashi
Julkaistu 2009

Epstein‐Barr virus‐positive gastric cancer involves enhancer activation through activating transcription factor 3

Tekijä Asakawa, Yuta, Okabe, Atsushi, Fukuyo, Masaki, Li, Wenzhe, Ikeda, Eriko, Mano, Yasunobu, Funata, Sayaka, Namba, Hiroe, Fujii, Takahiro, Kita, Kazuko, Matsusaka, Keisuke, Kaneda, Atsushi
Julkaisussa Cancer Sci (2020)

IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis

Tekijä Asano, Yoshinori, Kawase, Tatsuya, Okabe, Atsushi, Tsutsumi, Shuichi, Ichikawa, Hitoshi, Tatebe, Satoko, Kitabayashi, Issay, Tashiro, Fumio, Namiki, Hideo, Kondo, Tadashi, Semba, Kentaro, Aburatani, Hiroyuki, Taya, Yoichi, Nakagama, Hitoshi, Ohki, Rieko
Julkaisussa Sci Rep (2016)

Novel p53 target gene FUCA1 encodes a fucosidase and regulates growth and survival of cancer cells

Tekijä Ezawa, Issei, Sawai, Yuichiro, Kawase, Tatsuya, Okabe, Atsushi, Tsutsumi, Shuichi, Ichikawa, Hitoshi, Kobayashi, Yuka, Tashiro, Fumio, Namiki, Hideo, Kondo, Tadashi, Semba, Kentaro, Aburatani, Hiroyuki, Taya, Yoichi, Nakagama, Hitoshi, Ohki, Rieko
Julkaisussa Cancer Sci (2016)

PHLDA1, another PHLDA family protein that inhibits Akt

Tekijä Chen, Yu, Takikawa, Masahiro, Tsutsumi, Shuichi, Yamaguchi, Yoko, Okabe, Atsushi, Shimada, Mayuna, Kawase, Tatsuya, Sada, Akane, Ezawa, Issei, Takano, Yuhei, Nagata, Kisaburo, Suzuki, Yutaka, Semba, Kentaro, Aburatani, Hiroyuki, Ohki, Rieko
Julkaisussa Cancer Sci (2018)

Region-specific alteration of histone modification by LSD1 inhibitor conjugated with pyrrole-imidazole polyamide

Tekijä Alagarswamy, Kokiladevi, Shinohara, Ken-Ichi, Takayanagi, Shihori, Fukuyo, Masaki, Okabe, Atsushi, Rahmutulla, Bahityar, Yoda, Natsumi, Qin, Rui, Shiga, Naoki, Sugiura, Masahiro, Sato, Hiroaki, Kita, Kazuko, Suzuki, Takayoshi, Nemoto, Tetsuhiro, Kaneda, Atsushi
Julkaisussa Oncotarget (2018)

SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence

Tekijä Johmura, Yoshikazu, Sun, Jia, Kitagawa, Kyoko, Nakanishi, Keiko, Kuno, Toshiya, Naiki-Ito, Aya, Sawada, Yumi, Miyamoto, Tomomi, Okabe, Atsushi, Aburatani, Hiroyuki, Li, ShengFan, Miyoshi, Ichiro, Takahashi, Satoru, Kitagawa, Masatoshi, Nakanishi, Makoto
Julkaisussa Nat Commun (2016)

Tumor Suppressor miR-22 Determines p53-Dependent Cellular Fate through Post-transcriptional Regulation of p21

Tekijä Tsuchiya, Naoto, Izumiya, Masashi, Ogata-Kawata, Hiroko, Okamoto, Koji, Fujiwara, Yuko, Nakai, Makiko, Okabe, Atsushi, Schetter, Aaron J., Bowman, Elise D., Midorikawa, Yutaka, Sugiyama, Yasuyuki, Aburatani, Hiroyuki, Harris, Curtis C., Nakagama, Hitoshi
Julkaisussa Cancer Res (2011)

TET1 upregulation drives cancer cell growth through aberrant enhancer hydroxymethylation of HMGA2 in hepatocellular carcinoma

Tekijä Shirai, Kiyokazu, Nagae, Genta, Seki, Motoaki, Kudo, Yotaro, Kamio, Asuka, Hayashi, Akimasa, Okabe, Atsushi, Ota, Satoshi, Tsutsumi, Shuichi, Fujita, Takanori, Yamamoto, Shogo, Nakaki, Ryo, Kanki, Yasuharu, Osawa, Tsuyoshi, Midorikawa, Yutaka, Tateishi, Keisuke, Ichinose, Masao, Aburatani, Hiroyuki
Julkaisussa Cancer Sci (2021)

Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer

Tekijä Sugiura, Masahiro, Sato, Hiroaki, Okabe, Atsushi, Fukuyo, Masaki, Mano, Yasunobu, Shinohara, Ken-ichi, Rahmutulla, Bahityar, Higuchi, Kosuke, Maimaiti, Maihulan, Kanesaka, Manato, Imamura, Yusuke, Furihata, Tomomi, Sakamoto, Shinichi, Komiya, Akira, Anzai, Naohiko, Kanai, Yoshikatsu, Luo, Jun, Ichikawa, Tomohiko, Kaneda, Atsushi
Julkaisussa Transl Oncol (2020)